Results 241 to 250 of about 38,315 (266)
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ErbB receptors: new insights on mechanisms and biology

Trends in Cell Biology, 2006
The ErbB family of four receptor tyrosine kinases occupies a central role in a wide variety of biological processes from neuronal development to breast cancer. New information continues to expand their biologic significance and to unravel the molecular mechanisms that underlie the signaling capacity of these receptors.
Graham Carpenter, Bryan Linggi
openaire   +2 more sources

Bidirectional signaling of ErbB and Eph receptors at synapses

Neuron Glia Biology, 2008
Synapse development and remodeling are regulated by a plethora of molecules such as receptor tyrosine kinases (RTKs), a family of cell surface receptors that play critical roles in neural development. Two families of RTKs implicated in synaptic functions, ErbBs and Ephs, share similar characteristics in terms of exhibiting forward and reverse signaling.
Chen, Yu BICH, Fu, Kit Yu, Ip, Nancy Y.
openaire   +4 more sources

EGF/ErbB Receptor Family in Ovarian Cancer

2002
In summary, the EGF/ErbB family of receptor tyrosine kinases has been shown to play a key role in normal ovarian follicle development, and cell growth regulation of the ovarian surface epithelium. Disregulation of these normal growth regulatory pathways, including overexpression and/or mutation of EGFR/ErbB receptor family members, as well as elements ...
Nita J. Maihle   +12 more
openaire   +3 more sources

Nuclear ErbB Receptors: Pathways and Functions

2008
Accumulating evidence suggests a new mode of ErbB receptor signaling in which intact or fragmented ErbB receptors traffic from the cell surface to the nucleus following the addition of a cognate ligand. In the nucleus, ErbB receptors have a role, probably indirect, in modulating gene expression.
Hong-Jun Liao, Graham Carpenter
openaire   +2 more sources

Molecular Recognition in Water Using Macrocyclic Synthetic Receptors

Chemical Reviews, 2021
Luis Escobar, Pablo Ballester
exaly  

Treatment of renal cell carcinoma: Current status and future directions

Ca-A Cancer Journal for Clinicians, 2017
Pedro Barata, Brian I Rini
exaly  

Recent Progress in the Management of Advanced Renal Cell Carcinoma

Ca-A Cancer Journal for Clinicians, 2007
Brian I Rini
exaly  

Structural diversity of G protein-coupled receptors and significance for drug discovery

Nature Reviews Drug Discovery, 2008
Malin C Lagerström, Helgi B Schiöth
exaly  

REV-ERB and ROR nuclear receptors as drug targets

Nature Reviews Drug Discovery, 2014
Giuseppe Lippi   +2 more
exaly  

Muscarinic acetylcholine receptors: novel opportunities for drug development

Nature Reviews Drug Discovery, 2014
Andrew C Kruse   +2 more
exaly  

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