Results 241 to 250 of about 38,315 (266)
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ErbB receptors: new insights on mechanisms and biology
Trends in Cell Biology, 2006The ErbB family of four receptor tyrosine kinases occupies a central role in a wide variety of biological processes from neuronal development to breast cancer. New information continues to expand their biologic significance and to unravel the molecular mechanisms that underlie the signaling capacity of these receptors.
Graham Carpenter, Bryan Linggi
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Bidirectional signaling of ErbB and Eph receptors at synapses
Neuron Glia Biology, 2008Synapse development and remodeling are regulated by a plethora of molecules such as receptor tyrosine kinases (RTKs), a family of cell surface receptors that play critical roles in neural development. Two families of RTKs implicated in synaptic functions, ErbBs and Ephs, share similar characteristics in terms of exhibiting forward and reverse signaling.
Chen, Yu BICH, Fu, Kit Yu, Ip, Nancy Y.
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EGF/ErbB Receptor Family in Ovarian Cancer
2002In summary, the EGF/ErbB family of receptor tyrosine kinases has been shown to play a key role in normal ovarian follicle development, and cell growth regulation of the ovarian surface epithelium. Disregulation of these normal growth regulatory pathways, including overexpression and/or mutation of EGFR/ErbB receptor family members, as well as elements ...
Nita J. Maihle+12 more
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Nuclear ErbB Receptors: Pathways and Functions
2008Accumulating evidence suggests a new mode of ErbB receptor signaling in which intact or fragmented ErbB receptors traffic from the cell surface to the nucleus following the addition of a cognate ligand. In the nucleus, ErbB receptors have a role, probably indirect, in modulating gene expression.
Hong-Jun Liao, Graham Carpenter
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Molecular Recognition in Water Using Macrocyclic Synthetic Receptors
Chemical Reviews, 2021Luis Escobar, Pablo Ballester
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Treatment of renal cell carcinoma: Current status and future directions
Ca-A Cancer Journal for Clinicians, 2017Pedro Barata, Brian I Rini
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Recent Progress in the Management of Advanced Renal Cell Carcinoma
Ca-A Cancer Journal for Clinicians, 2007Brian I Rini
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Structural diversity of G protein-coupled receptors and significance for drug discovery
Nature Reviews Drug Discovery, 2008Malin C Lagerström, Helgi B Schiöth
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REV-ERB and ROR nuclear receptors as drug targets
Nature Reviews Drug Discovery, 2014Giuseppe Lippi+2 more
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Muscarinic acetylcholine receptors: novel opportunities for drug development
Nature Reviews Drug Discovery, 2014Andrew C Kruse+2 more
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