Results 101 to 110 of about 25,843 (211)

Prevention and treatment of post‐endoscopic retrograde cholangiopancreatography cholangitis: Current evidence and future directions

open access: yesClinical and Translational Discovery, Volume 6, Issue 6, December 2026.
1. Prevention strategies should be stratified by preoperative cholangitis status. 2. For pre‐existing cholangitis, therapeutic antibiotics plus urgent drainage are essential; ENBD and stents show similar efficacy. 3. Early biliary drainage is the cornerstone of treatment; endoscopic drainage is preferred, with PTCD/EUS‐BD as second‐line. 4.
Hao‐Xin Chen, Jun Yao
wiley   +1 more source

Associations Between Liver Biomarkers and Clinical Outcomes in Patients With Primary Sclerosing Cholangitis: A Retrospective Real‐World Study

open access: yesLiver International Communications, Volume 7, Issue 4, December 2026.
ABSTRACT Background and Aims This retrospective observational study assessed whether liver biomarker levels and their temporal changes can predict clinical outcomes in patients with primary sclerosing cholangitis (PSC). Approach and Results Adults with any cholangitis diagnosis in the TriNetX Dataworks‐USA network during the study period (2011–2021 ...
Jun Xu   +10 more
wiley   +1 more source

Liver Injury Due to Hormonal Contraceptives in the Modern Era

open access: yesLiver International, Volume 46, Issue 12, December 2026.
ABSTRACT Background and Aims Hormonal agents and their association with liver injury remain a concern in clinical practice. This study aimed to characterise the biochemical and clinical features of hormonal agent‐associated liver injury and compare them with a control group of age‐ and gender‐matched cases of liver injury caused by non‐hormonal drugs ...
Raj Vuppalanchi   +56 more
wiley   +1 more source

Post‐ERCP Pancreatitis Complicated by Abdominal Compartment Syndrome in the Setting of Lemmel Syndrome: A Fatal Case Report

open access: yesClinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Abdominal compartment syndrome should be suspected early in severe post‐endoscopic retrograde cholangiopancreatography pancreatitis with abdominal distension, oliguria, respiratory deterioration, and shock. Routine intra‐abdominal pressure monitoring and timely decompressive surgery are critical, as delayed recognition may rapidly progress to ...
Omar Marouf   +3 more
wiley   +1 more source

The Existence and Significance of Early Chronic Pancreatitis Within the AP–RAP–CP Sequence

open access: yesUnited European Gastroenterology Journal, Volume 14, Issue 9, November 2026.
ABSTRACT Background We previously proposed that three or more episodes of acute pancreatitis (AP) without radiological evidence of CP constitute early chronic pancreatitis (ECP), but it remains unclear whether ECP represents advanced recurrent acute pancreatitis (RAP) or a distinct clinical stage.
Viktória Venglovecz   +17 more
wiley   +1 more source

Endoscopic Sphincterotomy Prior to Biliary Stenting for Malignant Biliary Obstruction: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

open access: yesJournal of Gastroenterology and Hepatology, Volume 41, Issue 11, Page 3348-3355, November 2026.
ABSTRACT Background and Aims ERCP‐guided biliary stenting is the usual palliative treatment for patients with unresectable malignant biliary obstruction (MBO). Previous studies suggested that ES prior to biliary stenting may not reduce the post‐ERCP pancreatitis (PEP) risk and may increase bleeding risk.
Sofia Coelho Meine   +5 more
wiley   +1 more source

Alcohol‐Associated Pancreatitis Confers Higher Risk of Advanced Liver Disease Than Alcohol Withdrawal Syndrome

open access: yesJournal of Gastroenterology and Hepatology, Volume 41, Issue 11, Page 3557-3566, November 2026.
ABSTRACT Background and Aim Alcohol‐associated liver disease frequently presents late as decompensated cirrhosis, representing a missed opportunity for intervention. Extrahepatic alcohol‐related presentations requiring acute care, such as alcohol‐associated pancreatitis and alcohol withdrawal syndrome, may identify heavy drinkers at varying risk for ...
Butros Fakhoury   +5 more
wiley   +1 more source

PSC‐DM: A Validated Clinical Diagnostic Model for Distinguishing Primary From Secondary Sclerosing Cholangitis

open access: yesLiver International, Volume 46, Issue 11, November 2026.
ABSTRACT Background and Aims Primary sclerosing cholangitis (PSC) is a rare, progressive cholangiopathy for which diagnosis remains challenging because of the absence of disease‐specific markers and the presence of secondary causes of sclerosing cholangitis (SSC) that closely mimic its clinical presentation. Diagnostic uncertainty can delay appropriate
Miki Scaravaglio   +20 more
wiley   +1 more source

Pancreatic Cancer Early Detection Biomarkers for High‐Risk Individuals: Insights From the PRECEDE Consortium

open access: yesInternational Journal of Cancer, Volume 159, Issue 8, Page 1873-1883, 15 October 2026.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers due to its asymptomatic progression, late‐stage diagnosis, and treatment resistance. Efforts in early detection have centered on identifying imaging features and liquid biopsy biomarkers capable of detecting PDAC and its high‐grade precursors before clinical symptoms ...
Christine Worthington   +105 more
wiley   +1 more source

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