Abstract Background A drug designed for a specific target often interacts with multiple targets, either unintentionally or as part of its intended mechanism of action. This has been called pharmacological pleiotropy or polypharmacology. There are key endogenous ligands such as ATP, GABA and glutamate that act on various proteins in humans. Furthermore,
Hampus Ljunggren +8 more
wiley +1 more source
Endothelial Dysfunction and Erectile Dysfunction: Evidence From EASIX Score in NHANES 2001-2004. [PDF]
Cheng P, Li ZQ, Shen YJ, Xu W.
europepmc +1 more source
Vardenafil in the multidisciplinary management of erectile dysfunction: a narrative review on multidimensional outcomes and clinical integration. [PDF]
Zhou J, Hu S, Ouyang Y, Kong Y, Liu M.
europepmc +1 more source
ABSTRACT Aim To explore concerns and coping experiences regarding sexual well‐being in inflammatory bowel disease and examine the relationship between these concerns and affected individuals' background factors. Design Explanatory sequential mixed methods study.
Sayaka Wakai +3 more
wiley +1 more source
Predictors of successful erectile function using intracavernosal injection in post-prostatectomy men with erectile dysfunction. [PDF]
Veredgorn Y +6 more
europepmc +1 more source
The relationship between atherogenic index of plasma and erectile dysfunction: a cross-sectional observational study. [PDF]
Turkoglu AR +9 more
europepmc +1 more source
[68Ga]Ga‐PSMA‐11 PET/CT for baseline staging of high‐risk prostate cancer: A real‐world study
Abstract Objective To use real‐world data to determine the clinical risk factors that are predictive of metastatic disease in high‐risk prostate cancer (PCa) patients undergoing staging [68Ga]Ga‐Prostate‐Specific Membrane Antigen (PSMA)‐11 positron emission tomography combined with computed tomography (PET/CT). Methods Subjects with newly diagnosed PCa
Amy Rose Sharkey +9 more
wiley +1 more source
Prevalence of erectile dysfunction among healthy and sexually active Malaysian men aged 18 to 39 years. [PDF]
Hs AS +7 more
europepmc +1 more source
1H MR‐based detection of human plasma metabolic alterations in clear cell renal cell carcinoma
Abstract Objectives This study aimed to evaluate the potential of plasma‐based proton magnetic resonance spectroscopy (1H‐MRS) for non‐invasive discrimination between clear cell renal cell carcinoma (ccRCC), benign renal masses (angiomyolipoma and oncocytoma) and healthy controls by identifying disease‐specific metabolic signatures.
Raj Kumar Sharma +6 more
wiley +1 more source

