Results 241 to 250 of about 56,541 (297)

A Theoretical Model for the Treatment of Androgenetic Alopecia Using the STEAP3 Protein, and the Genetic Challenges of Treating AGA

open access: yesHealth Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Androgenetic alopecia (AGA) is a prevalent condition. The treatment methods currently available for this condition have limited potential (minoxidil) and side effects with long‐term therapy that affect the physiology of the male population (5α‐reductase inhibitors).
Ignacy Klemens Młodzianowski   +4 more
wiley   +1 more source

Metastasis‐Directed Surgery for Solitary Pulmonary Metastasis After Pembrolizumab in Urothelial Carcinoma: A Case Report

open access: yesIJU Case Reports, Volume 9, Issue 4, July 2026.
ABSTRACT Introduction The role of metastasis‐directed therapy in urothelial carcinoma remains uncertain, particularly in the immune checkpoint inhibitor era. We report a case of solitary pulmonary metastasis that developed after a favorable response to pembrolizumab and was managed with metastasectomy.
Kohji Takemura   +8 more
wiley   +1 more source

Varicocelectomy Restores Spermatogenesis in Fontan‐Associated Varicocele: A Two‐Case Series

open access: yesIJU Case Reports, Volume 9, Issue 4, July 2026.
ABSTRACT Introduction Fontan circulation may cause chronic venous hypertension and predispose patients to varicocele and infertility, but the clinical significance of surgical treatment remains unclear. Case Presentation We describe two patients with Fontan circulation who developed Fontan‐associated varicocele (FAVC).
Yusuke Tominaga   +9 more
wiley   +1 more source

Therapeutic Effect of Zingerone on Reproductive Damage in Diabetic Male Rats: Potential Role of Sirt1/Nrf2/HO‐1 and Bax/Bcl‐2 Signaling Pathways

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.
Diabetes mellitus causes significant damage to the male reproductive system. Sirt1/Nrf2/HO‐1 signaling pathway acts as a line of defense against ROS in reproductive organs. In STZ‐induced diabetic rats, the proapoptotic Bax protein expression was found to be elevated, whereas the antiapoptotic Bcl‐2 protein expression was reduced.
Edanur Güler Ekmen   +3 more
wiley   +1 more source

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