Results 221 to 230 of about 35,533 (292)

New biosensors and transgenic mice for multiplex cGMP imaging

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a versatile second messenger that is important for human (patho‐)physiology and pharmacotherapy. Live‐cell imaging of cGMP with biosensors allows to elucidate its spatiotemporal dynamics in real time under close‐to‐native conditions. However, to monitor two separate cGMP pools or cGMP/cAMP
Markus Wolters, Martin Thunemann, Barbara Birk, Susanne Feil, Viacheslav O. Nikolaev, Moritz Lehners, Robert Feil   +6 more
wiley   +1 more source

Liver transplantation improves erectile function in patients with end-stage liver disease: a systematic review and meta-analysis. [PDF]

Transl Androl Urol
Mei Y, Wang X, Li Y, Xu R, Feng X.
europepmc   +1 more source

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz, Sophie Sprenger, Olga Schweigert, Sanika Mohagaonkar, Matti Walsdorff, Tanja Zeller, Filip Berisha, Viacheslav O. Nikolaev, Sergei D. Rybalkin   +8 more
wiley   +1 more source

Analysis of the International Index of Erectile Function: psychometric evidence and measurement invariance across relationship status and age generations in a Chilean sample. [PDF]

Sex Med
Quintana GR, Ponce FP, Escudero-Pastén J, Santibáñez-Palma JF, Aguayo-Zuñiga CP, Carrasco-Portiño M, Cid-Aguayo M, González-Arias M, Ilabaca P, Jarpa-Schäcker R, López-Labarca C, Marrodán MA, Ramos N, Reyes-Torres L, Rosales-Pincetti V, Solis-Soto MT, Wlodarczyk A, Barrientos J.   +17 more
europepmc   +1 more source

Prioritizing bat roosts for conservation with a global multicriteria bat roost priority index based on community science

Conservation Biology, EarlyView.
Abstract Prioritization in conservation is crucial for the development of efficient and effective decision‐making policies. For many decades, the importance of some species and their habitats has been assessed and applied in conservation legislation, but bats and their diurnal roosts have ofbeen overlooked.
David López‐Bosch, Krizler Tanalgo, Xavier Puig‐Montserrat, Ferran Páramo, Eric Marín, Carles Flaquer, Adrià López‐Baucells   +6 more
wiley   +1 more source

Vascularised Brain Organoids: Engineering Strategies and Neurobiological Applications

Cell Proliferation, EarlyView.
This review highlights emerging strategies to engineer vascularized brain organoids—including endothelial co‐culture, genetic induction, perfusion systems, and in vivo transplantation—and their applications in modelling neurovascular diseases, evaluating BBB drug delivery, and advancing regenerative medicine.
Yeajin Song, Hyejin Jo, Seokchan Jeong, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

Composition Characterization of Cinnamomum osmophloeum Kanehira Hydrosol and Its Enhanced Effects on Erectile Function. [PDF]

Plants (Basel)
Wang CH, Taso NW, Chen CJ, Chang HY, Wang SY.   +4 more
europepmc   +1 more source

(115) DISORDERS OF THYROID FUNCTION AND ERECTILE DYSFUNCTION [PDF]

Marek Broul, Eva Jozífková, Dr Petra Kučerová   +2 more
openalex   +1 more source

Strategic materials and state capacity in Renaissance Italy. The economic policies of ‘Roman saltpetre’ procurement

The Economic History Review, EarlyView.
Abstract Demonstrating the existence of a soaring demand for strategic materials in fifteenth‐century Rome, the article pioneers research in the late medieval trade in saltpetre, the irreplaceable, rare component of gunpowder, indispensable for waging war following the diffusion of artillery technology.
Fabrizio Antonio Ansani
wiley   +1 more source

Long-term outcomes of erectile function in adult orchidopexy patients. [PDF]

Asian J Urol
Ghanem MA, Adawi EA, Ghanem AM, Ghanem AA.   +3 more
europepmc   +1 more source