Results 151 to 160 of about 84,102 (243)

Beyond Neovascularization: Light Response Deficits in Oxygen-Induced Retinopathy Models. [PDF]

Invest Ophthalmol Vis Sci
Becker S.
europepmc   +1 more source

Tonotopically distinct OFF responses arise in the mouse auditory midbrain following sideband suppression

The Journal of Physiology, EarlyView.
Abstract figure legend Sounds of different frequencies elicit spatially distinct patterns of neural activity within the inferior colliculus aligned to the tonotopic organization of afferent projections. Sound‐evoked neural responses can be visualized in awake mice that express fluorescent Ca2+ sensors.
Patrick D. Parker, Amanda M. Lauer, Dwight E. Bergles   +2 more
wiley   +1 more source

A ligandable PNT domain establishes ERG as a directly targetable oncogenic driver in prostate cancer. [PDF]

Proc Natl Acad Sci U S A
Wang X, Liu W, Yang J, Tien JC, Chang Y, Mannan R, Mahapatra S, Zhou Y, Gan L, Cao X, Zhou J, Zhang Y, Shaker S, Huang Y, Qiao H, Hamadeh R, Ervine G, Wang C, Su F, Wang R, Xiao L, Sudharshan RR, Rao A, Nikolovska-Coleska Z, Stephens C, Pan L, Chou JJ, Sahu D, Stuckey J, Wang Z, Ding K, Chinnaiyan AM.   +31 more
europepmc   +1 more source

Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes

The Journal of Physiology, EarlyView.
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière, Thomas Boulin, Maëlle Jospin, Alexandre Janin, Gilles Millat, Philippe Chevalier, Olga Andrini   +6 more
wiley   +1 more source

ERG preserves endothelial identity to limit atherosclerosis. [PDF]

Nat Commun
Botts SR, Scipione CA, Schulz K, Breda LCD, Ellis K, Ho C, Raju S, Prajapati K, Yu K, Khan AB, Polenz CK, Prattas SZ, Hyduk SJ, Cao C, Wythe JD, Robbins CS, Miller CL, Cybulsky MI, Fish JE, Howe KL.   +19 more
europepmc   +1 more source

Sustained Plus Lens Defocus Alters Retinal Responses and Ciliary Muscle Morphology In Myopes and Near-emmetropes. [PDF]

Ophthalmic Physiol Opt
Wagner S, Sommer C, Häupler S, Woll K, Strasser T.   +4 more
europepmc   +1 more source

Voltage‐gated potassium channels mediate thyroid hormone control of skeletal muscle excitability

The Journal of Physiology, EarlyView.
Abstract figure legend Thyroid hormone (TH)‐dependent remodelling of potassium (K+) channel networks regulates skeletal muscle (SkM) excitability. Triiodothyronine (T3), locally generated from thyroxine (T4) by type 2 deiodinase (D2), binds thyroid hormone receptors (TRα/β) and modulates transcription via thyroid response elements (TREs).
Annarita Nappi, Caterina Miro, Annunziata Gaetana Cicatiello, Ilaria Piccialli, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Rosa Sirica, Melania Murolo, Emery Di Cicco, Daniela Terracciano, Anna Pannaccione, Monica Dentice   +12 more
wiley   +1 more source

Multifocal intraosseous pseudomyogenic (epithelioid sarcoma-like) hemangioendothelioma: A rare presentation of an uncommon tumor

Indian Journal of Pathology and Microbiology
Pseudomyogenic hemangioendothelioma (PHE) is an uncommon mesenchymal neoplasm of intermediate malignant potential showing endothelial differentiation. Around 20 cases of primary osseous PHE have been reported to date.
Vishwapriya M. Godkhindi, Vidya Monappa, Sharada Mailankody, Umesh Velu, Shuiab M. V. Mohammed, Aisharya Banerjee   +5 more
doaj  

Three Progressive Upper Trunk Nodules: A Quiz. [PDF]

Acta Derm Venereol
Reiser S, Linse KP.
europepmc   +1 more source

Disseminated Angiosarcoma With Multifocal Small‐Bowel Involvement Presenting as Suspected Small‐Bowel Bleeding

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Angiosarcoma is a rare, aggressive vascular malignancy, and gastrointestinal involvement is uncommon. We report disseminated angiosarcoma with multifocal small‐bowel involvement presenting as suspected small‐bowel bleeding, in which small‐bowel capsule endoscopy (SBCE) and double‐balloon endoscopy (DBE) were diagnostically useful. A man in his
Mayu Tomita, Takashi Tashiro, Yoshiharu Yamaguchi, Kazunori Adachi, Masahide Ebi, Naotaka Ogasawara, Makoto Sasaki, Akana Hinokimoto, Toyonori Tsuzuki, Masanao Nakamura   +9 more
wiley   +1 more source