Results 191 to 200 of about 84,102 (243)

Ineffectiveness of immune checkpoint inhibitors in prostate cancer: is it just a question of ‘‐mabs’?

The Journal of Pathology, Volume 270, Issue 2, Page 139-162, October 2026.
Abstract Prostate cancer (PCa) is the second most common type of neoplasm, currently treated with a variety of therapeutic agents. Although advances in treatment over the past decade have improved overall survival, patients with advanced PCa eventually progress from hormone‐sensitive PCa to metastatic castration‐resistant PCa.
Giuseppe Schepisi, Irene Torresan, Emilio Francesco Giunta, Sara Bleve, Nicole Brighi, Elisa Tassinari, Sofia Zanuccoli, Maria Concetta Cursano, Cristian Lolli   +8 more
wiley   +1 more source

Effect of Minimizing Light Exposure with Digital Visualization on Macular Function After Cataract Surgery in Patients with AMD: A Randomized Controlled Trial. [PDF]

J Clin Med
Sandali O, Tahiri Joutei Hassani R, Audo I, Gualino V, Tchikladze Merand C, Borderie V.   +5 more
europepmc   +1 more source

Optical genome mapping enhanced by refined variant interpretation in pediatric acute lymphoblastic leukemia

The Journal of Pathology, Volume 270, Issue 2, Page 241-254, October 2026.
Abstract Reliable detection of structural variants (SVs) and copy number variations (CNVs) is crucial in the contemporary diagnostics of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). However, limitations of commonly used conventional and molecular cytogenetic methods may hinder the accurate genetic characterization of patients.
Anna Bekő, Borbála Péterffy, Alex Hughes, Janka Sára Jakab, Irén Haltrich, Kristóf Balázs Árvai, Gábor Bedics, Katalin Csonka, Gergő Papp, Dóra Kapczár, Bettina Aranka Bohusné Barta, Lajos László Hegyi, Gábor Szalóki, Gábor Barna, András Matolcsy, Bálint Egyed, Zsuzsanna Hevessy, Anne Benard‐Slagter, Sander Palit, Suvi Savola, Csaba Bödör, Donát Alpár   +21 more
wiley   +1 more source

AML with t(16;21)(p11.2;q22)/FUS::ERG rearrangement presenting with hemophagocytes and multinucleated cells: a case report and literature review. [PDF]

Ann Hematol
Chen Y, XinhongYang, Zhang Z, Yang X.
europepmc   +1 more source

Identification and Discrimination of Sulfated and Unsulfated Gut‐Hormone Biomarkers in Human Serum by Nanopore

Small, Volume 22, Issue 55, 1 October 2026.
This study discriminates between sulfated and unsulfated cholecystokinin‐8 gut‐hormone forms at single‐molecule‐level resolution. Using an aerolysin nanopore embedded in a hybrid lipid‐polymer membrane, the system produces distinct electrical signatures enabling highly sensitive detection, even in 20% human serum.
Luca Iesu, Laurent Bacri, Juan Pelta, Benjamin Cressiot   +3 more
wiley   +1 more source

Development and implementation of a project-based laboratory module: heterologous expression and fermentation of ergothioneine in <i>E. coli</i> for undergraduate biochemistry and molecular biology education. [PDF]

J Microbiol Biol Educ
Li L, Jiang Y.
europepmc   +1 more source

Faint Diffuse 557.7‐nm Emissions Equatorward of the Auroral Oval: Conjugate Observations by Ground Airglow Imagers and the Arase Satellite

Journal of Geophysical Research: Space Physics, Volume 131, Issue 10, October 2026.
Abstract At subauroral latitudes, discrete auroras, such as strong thermal emission velocity enhancement and stable auroral red arcs, have been extensively studied. On the other hand, diffuse emissions at subauroral latitudes have not been studied well.
M. Gomi, K. Shiokawa, Y. Miyoshi, Y. Otsuka, S. Oyama, M. Connors, A. Shinbori, T. Hori, C.‐W. Jun, K. Yamamoto, I. Shinohara, K. Asamura, S. Kasahara, K. Keika, S. Yokota, F. Tsuchiya, A. Kumamoto, Y. Kasahara, S. Matsuda, Y. Kazama, S.‐Y. Wang, S. W. Y. Tam, T.‐F. Chang, B.‐J. Wang, A. Matsuoka, M. Teramoto   +25 more
wiley   +1 more source

High-Level Production of Ergothioneine in Yarrowia lipolytica via Systematic Metabolic Engineering Strategies. [PDF]

Biotechnol Bioeng
Chen Q, Li J, Liu K, Wu Y, Li X, Zhang L, Guo D.   +6 more
europepmc   +1 more source

Muscarinic agonists for schizophrenia: Bridging preclinical evidence and clinical enthusiasm

British Journal of Pharmacology, Volume 183, Issue 19, Page 5701-5731, October 2026.
Abstract Antipsychotic drugs targeting dopamine receptors have been used to treat schizophrenia for decades, primarily alleviating positive symptoms such as hallucinations and delusions. However, they provide limited benefit for cognitive and negative symptoms—major contributors to poor outcomes—and are frequently associated with significant side ...
Brian J. Morris, Judith A. Pratt
wiley   +1 more source

Biological and pathogenic roles of major genes harbored in intrachromosomal amplification of chromosome 21 in childhood acute lymphoblastic leukemia (Review). [PDF]

Oncol Lett
Uría-Gómez CE, Mendieta-Zerón H, Arteaga-Vázquez J, Sandoval-Cabrera A.   +3 more
europepmc   +1 more source