Results 51 to 60 of about 84,102 (243)

Effect of Pupil Size on Fixed-Luminance Flicker Full-Field Electroretinogram Magnitude

open access: yesClinical Ophthalmology, 2022
Azadeh Mobasserian,1,* Moosa Zaidi,1,* Sohail Halim,1,2 Jaclyn Joyce Hwang,1 Jonathan Regenold,1 Amir Akhavanrezayat,1 Irmak Karaca,1,3 Hassan Khojasteh Jafari,1 Negin Yavari,1 Wataru Matsumiya,1,4 Cigdem Yasar,1,5 Ngoc Tuong Trong Than,1 Gunay ...
Mobasserian A   +15 more
doaj  

An Adult Presentation of KIF11‐Related MCLID Syndrome: Case Report and 40‐Year Follow‐Up

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Pathogenic variants in KIF11 are linked to autosomal dominant syndromes with microcephaly, chorioretinopathy, lymphedema, and intellectual disability (MCLID), though adult presentations remain underreported. We report a 42‐year‐old female presenting with a de novo single‐amino acid in‐frame deletion in the KIF11 gene (c.1294_1296del; p ...
Thrishna Chathurvedula   +8 more
wiley   +1 more source

A method for estimating intrinsic noise in electroretinographic (ERG) signals [PDF]

open access: yes, 2015
Purpose\ud \ud To develop a signal processing paradigm for extracting ERG responses to temporal sinusoidal modulation with contrasts ranging from below perceptual threshold to suprathreshold contrasts.
Hathibelagal, Amithavikram Rugvedi   +4 more
core   +1 more source

Chrysin attenuates diabetes‐induced retinal injury by inhibiting microglial GBP3/NLRP3/GSDMD‐mediated pyroptosis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We investigated the therapeutic potential and mechanism of chrysin in experimental diabetic retinal disease. Using a streptozotocin (STZ)‐induced diabetic mouse model and high‐glucose‐stimulated BV2 microglia, we revealed chrysin‐responsive pyroptosis‐associated signatures and identified GBP3 as a regulated node.
Qun Liu   +9 more
wiley   +1 more source

Molecular pathways driven by ETO2-GLIS2 in aggressive pediatric leukemia

open access: yesMolecular & Cellular Oncology, 2017
The ETO2-GLIS2 fusion oncoprotein is associated with poor prognosis pediatric acute megakaryoblastic leukemia. Recently, we observed that ETO2-GLIS2 controls enhancers activity at genes regulating haematopoietic progenitor self-renewal and ...
Cécile Thirant   +3 more
doaj   +1 more source

PDE9A is Expressed in the Inner Retina and Contributes to the Normal Shape of the Photopic ERG Waveform

open access: yesFrontiers in Molecular Neuroscience, 2014
The ubiquitous second messenger cGMP is synthesized by guanylyl cyclase and hydrolyzed by phosphodiesterase (PDE). cGMP mediates numerous signaling pathways in multiple tissues. In the retina, cGMP regulates signaling in nearly every cell class including
Anuradha eDhingra   +3 more
doaj   +1 more source

Tissue Expression of ETS-Related Gene in Gastric Carcinomas

open access: yesForbes Tıp Dergisi, 2020
INTRODUCTION: The ETS-related gene (ERG) encodes a member of the erythroblast transformation-specific (ETS) transcription factor family that has been implicated in both tumor invasion and neovascularization.
Sevil Sayhan   +4 more
doaj   +1 more source

Electroretinography in dogs: a review

open access: yesVeterinární Medicína, 2014
Electroretinography (ERG) in the form of full-field, flash ERG is the most commonly used technique in veterinary ophthalmology for diagnosing the functioning of the outer retina.
M. Drazek   +3 more
doaj   +1 more source

Development and Pilot-Scale Testing of Vibro-Briquetting Technology for Fine Chromite Raw Materials

open access: yesApplied Sciences
The processing of fine and technogenic chromite-bearing raw materials accumulated in tailings and sludge storage facilities is a key challenge for sustainable metallurgical development.
Maral Almagambetov   +5 more
doaj   +1 more source

Electroretinographic examination for evaluation of retinal activity in dogs with retinal dysplasia

open access: yesVeterinární Medicína, 2016
Individual types of retinal dysplasia - folds, geographic and detached, have different impacts on vision ability. The purpose of this study was to undertake a qualitative and comparative evaluation of retinal activity in the individual types of the ...
M. Drazek   +4 more
doaj   +1 more source

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