Results 191 to 200 of about 8,364 (289)

GNL3 Orchestrates AR Transcriptional Programs to Drive Castration‐Resistant Prostate Cancer and Immune Evasion

open access: yesAdvanced Science, Volume 13, Issue 26, 8 May 2026.
GNL3 is a novel AR coregulator with dual coactivator and corepressor functions in prostate cancer (PCa). Our study uncovers a previously unrecognized mechanism by which the AR transcriptional complex integrates oncogenic signaling and immune suppression.
Cuiting Zhang   +12 more
wiley   +1 more source

BCR::ABL1‐Induced Enhancer Reprogramming Uncovers Hypersensitivity of Ph+B‐ALL Cells to Enhancer‐Targeting Drugs

open access: yesAdvanced Science, Volume 13, Issue 25, 4 May 2026.
Ng et al. show that the BCR::ABL1 kinase that drives the lymphoid leukemia Ph+B‐ALL modulates enhancer function by coopting signaling‐inducible transcription factors such as MYC, STAT5, and ETV5. BCR::ABL1 thereby promotes the transcriptional program driving and defining this leukemia and renders Ph+B‐ALL cells hypersensitive to enhancer‐inhibiting ...
Han Leng Ng   +19 more
wiley   +1 more source

Synchronous Haemorrhagic Tumors of the Anterior Maxilla and Oropharynx

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
Photomicrograph of a low‐power view of partially ulcerated squamous mucosa with underlying vascular proliferation showing anastomosing vascular channels. Hematoxylin and eosin stain. Magnification ×20. ABSTRACT Oral epithelioid angiosarcoma arising in the oral cavity is exceptionally rare.
Brian Maloney   +5 more
wiley   +1 more source

Multifocal Benign Metastasizing Pleomorphic Adenoma Presenting as a Lymphoma: An Atypical Clinical Picture Demystified by an Unusual PLAG1 Gene Rearrangement Detected on RNA Next Generation Sequencing

open access: yesDiagnostic Cytopathology, Volume 54, Issue 5, Page E140-E145, May 2026.
ABSTRACT A 57‐year‐old female presented to urgent care with exertional dyspnea, back pain, and several months of night sweats. Imaging showed an anterior mediastinal mass with concurrent hepatic and vertebral lesions, raising suspicion for a hematolymphoid malignancy.
Poorva Singh   +3 more
wiley   +1 more source

An Evaluation of Longitudinal Thyroid Hormone Levels Over the Years Before and After Patients Started on Levothyroxine

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 3, May 2026.
Free thyroxine (FT4) median (interquartile range) and percentage FT4 within reference range for patients pre‐ and post‐levothyroxine (LT4) treatment versus untreated individuals. ABSTRACT Introduction This retrospective study aimed to investigate how free thyroxine (FT4) and thyroid‐stimulating hormone (TSH) levels change in the years pre‐ and post ...
Michael Stedman   +10 more
wiley   +1 more source

The neurophysiology of language processing shapes the evolution of grammar: evidence from case marking. [PDF]

open access: yesPLoS One, 2015
Bickel B   +4 more
europepmc   +1 more source

In Vivo Evaluation of Preconditioned Adipose‐Derived Stromal Cells Reveals Limited Impact on Vascular and ECM Remodeling in Polymer Scaffolds

open access: yesJournal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 5, May 2026.
ABSTRACT Polymer scaffolds are a promising platform for the transplantation of insulin‐producing cells in Type 1 Diabetes. While vascularization has been a primary focus due to its role in oxygen and nutrient delivery, the interplay between blood vessels and the extracellular matrix (ECM) is increasingly recognized as critical for establishing a stable
Erika Pinheiro‐Machado   +5 more
wiley   +1 more source

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