Results 141 to 150 of about 4,387 (238)
New cell lines expanding the diversity of Ewing sarcoma models
What's new? A chromosomal translocation between the EWSR1 and ETS genes is the key oncogenic driver in Ewing sarcoma. EWSR1::FLI1, the most frequent fusion, is subdivided into different fusion types with unclear prognostic relevance. Here, the authors describe the establishment and characterization of four new, intrinsically immortal, patient‐derived ...
Maximilian Kerkhoff +13 more
wiley +1 more source
Enduring constraints on grammar revealed by Bayesian spatiophylogenetic analyses. [PDF]
Verkerk A +7 more
europepmc +1 more source
ABSTRACT Introduction In Mexico, the 5‐year overall survival (OS) rate for pediatric acute lymphoblastic leukemia (ALL) ranges from 45% to 85%, markedly lower than the ∼90% reported in high‐income countries, where cytogenomic testing is essential for accurate risk stratification and therapeutic decision‐making.
Rosa María González Arreola +8 more
wiley +1 more source
A Gradualist Scenario for Language Evolution: Precise Linguistic Reconstruction of Early Human (and Neandertal) Grammars. [PDF]
Progovac L.
europepmc +1 more source
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
Hindi CCGbank: A CCG treebank from the Hindi dependency treebank. [PDF]
Ambati BR, Deoskar T, Steedman M.
europepmc +1 more source
Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian +8 more
wiley +1 more source
ABSTRACT Background Prostate cancer (PCa) is the most common solid organ cancer in men and the fifth leading cause of cancer‐related deaths globally. PSA helps identify men at risk but has low specificity and has resulted in unnecessary biopsies. The PROSTest, a novel machine learning‐based 27‐gene mRNA liquid biopsy assay, was developed to detect PCa.
Mark Kidd +5 more
wiley +1 more source
The resilience of structure built around the predicate: Homesign gesture systems in Turkish and American deaf children. [PDF]
Goldin-Meadow S +4 more
europepmc +1 more source

