Results 41 to 50 of about 255 (228)
Advanced Science, EarlyView.We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai +8 more
wiley +1 more source
Advanced Science, EarlyView.We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du +11 more
wiley +1 more source
Forma y Función, 2007 El afán de encontrar un criterio único-formal-universal para la identificación del sujeto -o de cualquier otra categoría gramatical-, como se da el caso en ciertas corrientes teóricas, es una postura que nos hace correr el riesgo o «de acostar las ...
Francesc Queixalós
doaj
A Violação da Condição em Kadiwéu Condition C Violation in Kadiwéu
DELTA: Documentação de Estudos em Lingüística Teórica e Aplicada, 2002 Apesar de o kadiwéu apresentar as mesmas características tipológicas das línguas analisadas por Baker (1995), este trabalho mostra que o parâmetro da polissíntese proposto por Baker, de acordo com o qual as línguas polissintéticas seriam línguas de ...
Filomena SANDALO
doaj +1 more source
Heat Shock Protein 90: From Molecular Chaperone Function to Therapeutic Targeting in Malignancies
Advanced Science, EarlyView.In this review, an integrated conceptual framework linking HSP90's molecular chaperone functions to its pathological roles in cancer is proposed. HSP90 serves as a central node that integrates oncogenic signaling, buffers proteotoxic stress, maintains cancer stem cell plasticity, and shapes tumor‐immune interactions, all of which converge to drive ...
Beibei Zhang +4 more
wiley +1 more source
Critical Approaches to Discourse Analysis across Disciplines, 2018 The paper examines the roles construed to migrants and to European states in Reuters and AP news agency reports autumn 2015 and spring 2016. In 2015, more than a million migrants came to Europe.
Maija Stenvall
doaj
An active analysis of Basque ergativity
Fontes Linguae Vasconum, 1999 Previous generative work on Basque syntax has attempted to equate either the NOR or the NORK case in Basque with a “subject case” corresponding structurally to nominative.
Arthur Holmer
doaj +1 more source
Streamlining Diagnosis of Bardet–Biedl Syndrome: New Diagnostic Algorithm With Updated Criteria
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Considerable advances have been made in our understanding of Bardet–Biedl syndrome (BBS), particularly in its core clinical features and molecular genetics, warranting an update to the existing diagnostic criteria framework. Using a rigorous, evidence‐based, and consensus‐driven process, a multidisciplinary group of international experts and ...
Jeremy J. Pomeroy +16 more
wiley +1 more source
Syntax: Its Evolution and Its Representation in the Brain
Biolinguistics, 2010 Poeppel (2008) observes that there is no clear correspondence between units of analysis in linguistics (especially the abstract and arbitrary-looking principles of syntax) and biological units of neuroscience, concluding that current neurolinguistic ...
Ljiljana Progovac
doaj +1 more source
Passivization in Taleshi dialect (of Sehsar) [PDF]
زبان پژوهی, 2019 This article surveys passivization in Taleshi dialect. This dialect is common in some areas of the Guilan province. This dialect, i.e Taleshi dialect, is divided into three different branches which are called central, northern and southern Taleshi ...
Abdullah Ezzat doust +2 more
doaj +1 more source