Results 1 to 10 of about 13,168 (257)

Ergotamine enhances circadian amplitude and diurnally mitigates nitroglycerin-induced mechanical hypersensitivity [PDF]

The Journal of Headache and Pain
Background Cluster headache and migraine have a circadian timing of attacks and are linked to the trigeminovascular system. Recently the trigeminal ganglion was found to have a strong circadian rhythm, with the serotonin 2A receptor identified as a clock-
Chorong Han, Hwayoung Baek, Ji Ye Lim, Eunju Kim, Celia K. Tran, Emma Freeman, Zheng Chen, Seung-Hee Yoo, Mark J. Burish   +8 more
doaj   +3 more sources

Combination ergotamine and caffeine improves seated blood pressure and presyncopal symptoms in autonomic failure [PDF]

Frontiers in Physiology, 2014
Severely affected patients with autonomic failure require pressor agents to counteract the blood pressure fall and improve presyncopal symptoms upon standing.
Amy C Arnold, Claudia E Ramirez, Leena eChoi, Luis E Okamoto, Alfredo eGamboa, André eDiedrich, Satish R Raj, David eRobertson, Italo eBiaggioni, Cyndya Adriana Shibao   +9 more
doaj   +3 more sources

First Synthesis of Ergotamine-¹³CD₃ and Ergotaminine-¹³CD₃ from Unlabeled Ergotamine [PDF]

Toxins
Ergot alkaloids (EAs) formed by Claviceps fungi are one of the most common food contaminants worldwide, affecting cereals such as rye, wheat, and barley.
Sven-Oliver Herter, Hajo Haase, Matthias Koch   +2 more
doaj   +3 more sources

Ergotamine Stimulates Human 5-HT4-Serotonin Receptors and Human H2-Histamine Receptors in the Heart [PDF]

International Journal of Molecular Sciences, 2023
Ergotamine (2′-methyl-5′α-benzyl-12′-hydroxy-3′,6′,18-trioxoergotaman) is a tryptamine-related alkaloid from the fungus Claviceps purpurea. Ergotamine is used to treat migraine.
Hannes Jacob, Pauline Braekow, Rebecca Schwarz, Christian Höhm, Uwe Kirchhefer, Britt Hofmann, Joachim Neumann, Ulrich Gergs   +7 more
openalex   +2 more sources

The Application of the Neuroprotective and Potential Antioxidant Effect of Ergotamine Mediated by Targeting N-Methyl-D-Aspartate Receptors

Antioxidants, 2022
(1) Background: The N-methyl-D-aspartate receptors (NMDARs) mediate fast excitatory currents leading to depolarization. Postsynaptic NMDARs are ionotropic glutamate receptors that mediate excitatory glutamate or glycine signaling in the CNS and play a ...
Shinhui Lee, Sanung Eom, Khoa V. A. Nguyen, Jiwon Lee, Youngseo Park, Hye Duck Yeom, Junho H. Lee   +6 more
doaj   +2 more sources

Effects of ergotamine on the central nervous system using untargeted metabolomics analysis in a mouse model

Scientific Reports, 2021
The ergot alkaloid ergotamine is produced by Claviceps purpurea, a parasitic fungus that commonly infects crops and pastures of high agricultural and economic importance.
Priyanka Reddy, Delphine Vincent, Joanne Hemsworth, Vilnis Ezernieks, Kathryn Guthridge, German C. Spangenberg, Simone J. Rochfort   +6 more
doaj   +2 more sources

Ergotamine and triptans induced medication-overuse headache: a real-world population-based comparative study from the Northern Thai headache registry [PDF]

The Journal of Headache and Pain
Background Medication-overuse headache (MOH) remains a leading cause of chronic daily headache globally. Although triptans are the predominant implicated in high-income countries, ergotamine continues to be widely used in many low- and middle-income ...
Surat Tanprawate, Kitti Thiankhaw, Watthikorn Chusilthong, Vipanee Muangchean, Sirinada Ma-imjai, Noratham Chalapati, Kanokkarn Teekaput, Chutithep Teekaput   +7 more
doaj   +2 more sources

A potentially lethal interaction: Migraine, human immunodeficiency virus and ergotism – A primary care case report [PDF]

Malaysian Family Physician
Ergotism is a rare but potentially serious condition characterised by peripheral vasospasm. Its diagnosis is challenging because the presentation varies depending on the type and location of the affected blood vessels.
Ahmad Sahli Mahzuz Ismail, Shaiful Bahari Ismail, Lili Husniati Yaacob   +2 more
doaj   +2 more sources

Effects of Psilocin and Psilocybin on Human 5-HT₄ Serotonin and H₂ Histamine Receptors in Perfused Hearts of Transgenic Mice [PDF]

Pharmaceuticals
Background/Objectives: Hallucinogenic substances such as psilocybin, psilocin, ergometrine, ergotamine, and lysergic acid diethylamide (LSD) have been demonstrated to enhance the force of contraction (FOC), in part due to the phosphorylation of ...
Pauline Braekow, Joachim Neumann, Uwe Kirchhefer, Ulrich Gergs   +3 more
doaj   +2 more sources

Acute coronary syndrome with elevation of ST associated with ergotamine abuse

Romanian Journal of Internal Medicine, 2019
There are few case reports of cases of carotid and aortic dissection related to the ergotamine abuse, but the cases that affect the coronary arteries is a very rare coronary.
Pérez Baztarrica Gabriel E., Armijos Carrion Leonardo P., Abarca Real Juan H., Paredes Lima William A., Giler Saltos Otto P., Porcile Rafeal   +5 more
doaj   +2 more sources