Results 11 to 20 of about 8,478 (179)

TLC densitometric approach for concurrent determination of quinary mixture for treatment of migraine with appraisal to method greenness and whiteness [PDF]

open access: yesScientific Reports
A new accurate, precise thin layer chromatographic (TLC densitometric) approach was developed for the simultaneous analysis of ergotamine tartrate (ERG), phenobarbital sodium (PHEN), caffeine anhydrous (CAF), dipyrone sodium (DIP) and meprobamate (MEP ...
Marco M. Z. Sharkawi   +3 more
doaj   +2 more sources

Unveiling nonribosomal peptide synthetases from the ergot fungus Claviceps purpurea involved in the formation of diverse ergopeptines [PDF]

open access: yesActa Pharmaceutica Sinica B
Ergopeptines or their derivatives are widely used for treating neurodegenerative and cerebrovascular diseases. The nonribosomal peptide synthetase—d-lysergyl peptide synthetase A (LPSA) determines ergopeptine formation but the detailed mechanism remains ...
Jing-Jing Chen   +5 more
doaj   +2 more sources

Coronary side-effect potential of current and prospective antimigraine drugs [PDF]

open access: yes, 1998
BACKGROUND: The antimigraine drugs ergotamine and sumatriptan may cause angina-like symptoms, possibly resulting from coronary artery constriction. We compared the coronary vasoconstrictor potential of a number of current
Bax, W.A. (Willem)   +4 more
core   +17 more sources

Selected plant materials used in migraine therapy [PDF]

open access: yesFarmacja Polska, 2023
Migraine is a neurovascular disease characterized by idiopathic, throbbing, usually unilateral headache, accompanied by gastrointestinal disturbances and increased sensitivity to stimuli. Symptoms may persist for several days, and their severity prevents
Joanna Piotrowska   +3 more
doaj   +1 more source

The Application of the Neuroprotective and Potential Antioxidant Effect of Ergotamine Mediated by Targeting N-Methyl-D-Aspartate Receptors

open access: yesAntioxidants, 2022
(1) Background: The N-methyl-D-aspartate receptors (NMDARs) mediate fast excitatory currents leading to depolarization. Postsynaptic NMDARs are ionotropic glutamate receptors that mediate excitatory glutamate or glycine signaling in the CNS and play a ...
Shinhui Lee   +6 more
doaj   +1 more source

Bioactive components and molecular mechanisms of Xiaoyao pill in the treatment of chloasma: based on integrated network pharmacology and bioinformatics methods

open access: yesPifu-xingbing zhenliaoxue zazhi, 2023
Objective To analyze the active ingredients of Xiaoyao Pill and its molecular mechanisms in the treatment of chloasma. Methods The active ingredients of Xiaoyao Pill, its target proteins and the targets related to human chloasma were searched through ...
Suyue PAN   +8 more
doaj   +1 more source

Quartz Crystal Microbalance Biosensor for Ergotamine Detection

open access: yesInternational Journal of Electrochemical Science, 2020
Ergotamine is a toxin from ergot fungi. It interacts with various receptors in the organisms including the one for adrenaline, serotonin and dopamine.
Miroslav Pohanka
doaj   +1 more source

Mycotoxin exposure assessments in a multi-center European validation study by 24-hour dietary recall and biological fluid sampling [PDF]

open access: yes, 2020
The European Food Consumption Validation (EFCOVAL) project includes 600 men and women from Belgium, the Czech Republic, France, the Netherlands, and Norway, who had given serum and 24-hour urine samples, and completed 24-hour dietary recall (24-HDR ...
Abbeddou, Souheila   +11 more
core   +1 more source

Drug-Induced Acrocyanosis: Highlighting Venlafaxine as a Potential Culprit. [PDF]

open access: yesClin Case Rep
Resolution of venlafaxine‐induced acral cyanosis following discontinuation of the drug. ABSTRACT Acrocyanosis is a peripheral vascular disorder characterized by bluish discoloration of the distal extremities. While drug‐induced acrocyanosis has been associated with selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants, and other ...
Manandhar S   +3 more
europepmc   +2 more sources

A Rapid and Sensitive Stability-Indicating Eco-Friendly HPTLC Assay for Fluorescence Detection of Ergotamine

open access: yesMolecules, 2023
Eco-friendly liquid chromatographic methods for measuring ergotamine (EGT) are scant in the published database. Accordingly, the goal of the current study was to develop a high-performance thin-layer chromatography (HPTLC) method for fluorescence ...
Faiyaz Shakeel   +5 more
doaj   +1 more source

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