Results 21 to 30 of about 8,701 (200)

First Synthesis of Ergotamine-<sup>13</sup>CD<sub>3</sub> and Ergotaminine-<sup>13</sup>CD<sub>3</sub> from Unlabeled Ergotamine. [PDF]

open access: yesToxins (Basel)
Ergot alkaloids (EAs) formed by Claviceps fungi are one of the most common food contaminants worldwide, affecting cereals such as rye, wheat, and barley.
Herter SO, Haase H, Koch M.
europepmc   +2 more sources

Selected plant materials used in migraine therapy [PDF]

open access: yesFarmacja Polska, 2023
Migraine is a neurovascular disease characterized by idiopathic, throbbing, usually unilateral headache, accompanied by gastrointestinal disturbances and increased sensitivity to stimuli. Symptoms may persist for several days, and their severity prevents
Joanna Piotrowska   +3 more
doaj   +1 more source

Bioactive components and molecular mechanisms of Xiaoyao pill in the treatment of chloasma: based on integrated network pharmacology and bioinformatics methods

open access: yesPifu-xingbing zhenliaoxue zazhi, 2023
Objective To analyze the active ingredients of Xiaoyao Pill and its molecular mechanisms in the treatment of chloasma. Methods The active ingredients of Xiaoyao Pill, its target proteins and the targets related to human chloasma were searched through ...
Suyue PAN   +8 more
doaj   +1 more source

Identification of potent TMPRSS4 inhibitors through structural modeling and molecular dynamics simulations. [PDF]

open access: yesSci Rep
TMPRSS4, a transmembrane serine protease type II, is associated with various pathological illnesses. It has been found to activate SARS-CoV-2, enhance viral infection of human small-intestinal enterocytes and is overexpressed in different types of ...
Hdoufane I   +5 more
europepmc   +2 more sources

Identifying potential drug targets in the kinomes of two monogenean species. [PDF]

open access: yesHelminthologia
Protein kinases are enzymes involved in essential biological processes such as signal transduction, transcription, metabolism, and the cell cycle. Human kinases are targets for several drugs approved by the US Food and Drug Administration. Therefore, the
Caña-Bozada VH   +4 more
europepmc   +2 more sources

A Rapid and Sensitive Stability-Indicating Eco-Friendly HPTLC Assay for Fluorescence Detection of Ergotamine

open access: yesMolecules, 2023
Eco-friendly liquid chromatographic methods for measuring ergotamine (EGT) are scant in the published database. Accordingly, the goal of the current study was to develop a high-performance thin-layer chromatography (HPTLC) method for fluorescence ...
Faiyaz Shakeel   +5 more
doaj   +1 more source

Ergotamine tartrate

open access: yesDefinitions, 2020
The tartrate salt form of ergotamine, an ergot alkaloid and adrenergic alpha agonist with vasoconstrictor activity. Ergotamine tartrate selectively binds to alpha-adrenergic receptors thereby stimulating vascular smooth muscle and causing ...
Ergotamine Tartrate
semanticscholar   +1 more source

TLC densitometric approach for concurrent determination of quinary mixture for treatment of migraine with appraisal to method greenness and whiteness. [PDF]

open access: yesSci Rep
A new accurate, precise thin layer chromatographic (TLC densitometric) approach was developed for the simultaneous analysis of ergotamine tartrate (ERG), phenobarbital sodium (PHEN), caffeine anhydrous (CAF), dipyrone sodium (DIP) and meprobamate (MEP ...
Sharkawi MMZ   +3 more
europepmc   +2 more sources

Effects of hallucinogenic drugs on the human heart. [PDF]

open access: yesFront Pharmacol
Hallucinogenic drugs are used because they have effects on the central nervous system. Their hallucinogenic effects probably occur via stimulation of serotonin receptors, namely, 5-HT2A-serotonin receptors in the brain.
Neumann J   +4 more
europepmc   +2 more sources

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