Results 41 to 50 of about 8,478 (179)
Iraqi Journal of Pharmaceutical Sciences, 2017 Free radicals and oxidative damage caused by them have being suggested to be involved in the pathogenesis of migraine. These may result from distorted equilibrium of pro-oxidant/anti-oxidant system that continuously generates and detoxifies oxidants ...
Shahlaa H. Ali +2 more
doaj +3 more sources
Drug Design, Development and Therapy, 2022 Dianna Liu,1 Shicheng Lin,2 Yuan Li,2 Tian Zhou,1 Kaiwen Hu,1 Quanwang Li1 1Oncology Department, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, 100071, People’s Republic of China; 2Graduate School, Beijing University of Chinese ...
Liu D, Lin S, Li Y, Zhou T, Hu K, Li Q
doaj
Migraine: Diagnosis, treatment and understanding c1960-2010 [PDF]
, 2014 seminar transcriptThere are around eight million migraine sufferers in the UK today. This Witness Seminar looked at the last 50 years of research into the diagnosis and treatment of the condition and the changing attitudes of the medical profession ...
Overy, C, Tansey, EM
core
Report on the 2017 Proficiency Test of the European Union Reference Laboratory for Mycotoxins: determination of ergot alkaloids in rye [PDF]
, 2017 Throughout history, there have been several deadly episodes of food poisoning by ergot alkaloids (EAs) (known as St. Anthony’s fire or ergotism). EAs are secondary metabolites produced by fungi of the Claviceps genus (chiefly Claviceps purpurea), which ...
BOUTEN KATRIEN +4 more
core +2 more sources
Preclinical models for evaluating psychedelics in the treatment of major depressive disorder
British Journal of Pharmacology, EarlyView.Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander +5 more
wiley +1 more source
, 1999 Migraine is a complex neurovascular disease characterised by episodic attacks of severe headache accompanied by autonomic and neurological symptoms. Two types of migraine have been identified: (1) common migraine, or migraine without aura, occurring in ...
Farrugia, Isabelle
core
Cyclopropanation of carbon-carbon double bonds in ring d of ergot alkaloids [PDF]
, 2013 Some ergot alkaloid derivatives containing a double bond in ring D have been reacted with diazomethane/palladium diacetate reagent to result in formation of a fused cyclopropane ring.
Dörnyei, Gábor +5 more
core +1 more source
Neuropsychopharmacology of hallucinogenic and non‐hallucinogenic 5‐HT2A receptor agonists
British Journal of Pharmacology, EarlyView.Psychedelic drugs such as LSD and psilocin were once relegated to the fringes of medical research because of their association with counterculture movements and a perceived concern about harm through recreational use, and their consequent legal prohibition in the early 1970s.
Trevor Sharp, Aurelija Ippolito
wiley +1 more source
Psychedelics, entactogens and psychoplastogens for depression and related disorders
British Journal of Pharmacology, EarlyView.Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley +1 more source
Coalescing beneficial host and deleterious antiparasitic actions as an antischistosomal strategy
eLife, 2018 Conventional approaches for antiparasitic drug discovery center upon discovering selective agents that adversely impact parasites with minimal host side effects.
John D Chan +2 more
doaj +1 more source