Results 1 to 10 of about 1,900 (208)

Gel-forming antagonist provides a lasting effect on CGRP-induced vasodilation. [PDF]

Front Pharmacol, 2022
Migraine affects ∼15% of the adult population, and the standard treatment includes the use of triptans, ergotamines, and analgesics. Recently, CGRP and its receptor, the CLR/RAMP1 receptor complex, have been targeted for migraine treatment due to their ...
Chang CL, Cai Z, Hsu SYT.
europepmc   +2 more sources

Trends in utilization and costs of migraine medications, 2017-2020. [PDF]

J Headache Pain, 2022
Objective This study examines changes in utilization and costs trends associated with migraine medications. Background Migraine attacks are a burden to many patients.
Nguyen JL, Munshi K, Peasah SK, Swart ECS, Kohli M, Henderson R, Good CB.   +6 more
europepmc   +2 more sources

Ergotamine-induced venous thrombosis [PDF]

Postgraduate Medical Journal, 1974
Summary A patient is described who developed venous thrombosis in the leg following an intramuscular injection of ergotamine tartrate.
S. Bar-Meir, A. De Vries, Uri Mintz
openaire   +4 more sources

Long-term reductions in acute headache medication use after eptinezumab treatment in patients with migraine and prior preventive treatment failures: Post hoc analysis of the DELIVER randomized trial. [PDF]

Headache
Abstract Objective To evaluate long‐term reductions in acute headache medication (AHM) use with eptinezumab versus placebo in patients with prior preventive migraine treatment failures and medication overuse (MO). Background Preventive migraine treatment is recommended for patients for whom AHMs have failed and for those who are using excessive amounts
Gryglas-Dworak A, Schim J, Ettrup A, Boserup LP, Josiassen MK, Ranc K, Sperling B, Ashina M.   +7 more
europepmc   +2 more sources

Seasonal Variations in Triptan Prescription in Japan: A Nationwide Time-Series Analysis. [PDF]

Brain Behav
The results of this study suggest that seasons can impact the onset of migraine. Thus, to reduce the amount of triptan prescriptions, clinicians may advise patients to take preventive actions, including self‐care and drug therapies from winter to reduce the number of migraine onsets in spring regardless of region. ABSTRACT Objective This study aimed to
Tatsumoto M, Hirata K, Nakayama T, Yamato K, Sano H, Inuyama L.   +5 more
europepmc   +2 more sources

Relative frequency, characteristics, and disease burden of patients with migraine unsuitable for triptan treatment: A systematic literature review. [PDF]

Headache
Abstract Objective This review was conducted to systematically identify evidence characterizing patients with migraine who are unsuitable for triptans. Background Triptans are not suitable as first‐line treatment for all patients with migraine due to contraindications, lack of efficacy, and/or poor tolerability.
Lipton RB, Gendolla A, Abraham L, Jenkins A, Telfort J, Blakeman KH, Saccone PA, Pustulka I, Fotheringham I, Engh A.   +9 more
europepmc   +2 more sources

Fungi and mycotoxins: Food contaminants [PDF]

Hemijska Industrija, 2013
The growth of fungi on food causes physical and chemical changes which, further affect negatively the sensory and nutritive quality of food. Species from genera: Aspergillus, Penicillium, Fusarium, Alternariа, Cladosporium, Mucor, Rhizopus, Eurotium ...
Kocić-Tanackov Sunčica D., Dimić Gordana R.   +1 more
doaj   +1 more source

Buccal absorption of ergotamine [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 1974
The rate of disappearance of ergotamine from the mouth after buccal administration has been studied in seven subjects. Allowance has been made for non-absorptive losses of the drug due to experimental technique. The absorption of ergotamine across the buccal mucosa appears to be a passive process, pH-dependent but independent of ergotamine ...
Sutherland J.M., Hooper W.D., Eadie M.J., Tyrer J.H.   +3 more
openaire   +4 more sources

Ergotamine absorption and toxicity [PDF]

Postgraduate Medical Journal, 1982
Abstract Adverse reactions to ergotamine were noted in 16 out of 41 studies in which therapeutic doses of the drug were given to normal, healthy volunteers. In 17 of the studies 0.25 mg ergotamine was given by injection, 6 i.v. and 11 i.m., in 20 studies 2 mg ergotamine was given by mouth, and 4 subjects received 2 mg ergotamine by ...
Rudy J. Richardson, D. A. Orton
openaire   +2 more sources

Acute medication overuse in headache [PDF]

Einstein (São Paulo), 2004
Primary headache patients frequently overuse analgesics. Acute medication overuse plays an important role in the transformation of episodic into chronic headaches.
Abouch Valenty Krymchantovscki
doaj