Results 21 to 30 of about 5,158 (243)

Grass-endophytes in plant protection [PDF]

open access: yes, 2009
Agriculturists have long known that certain grass species infected with systemic fungal endophytes are highly resistant to both vertebrate and invertebrate ...
Saikkonen, Kari
core  

Acute Treatments for Episodic Migraine in Adults: A Systematic Review and Meta-analysis.

open access: yesJournal of the American Medical Association (JAMA), 2021
Importance Migraine is common and can be associated with significant morbidity, and several treatment options exist for acute therapy. Objective To evaluate the benefits and harms associated with acute treatments for episodic migraine in adults. Data
J. VanderPluym   +14 more
semanticscholar   +1 more source

Drugs induced Raynaud's phenomenon and underlying mechanism: a disproportionality analysis from the WHO pharmacovigilance database

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives The aim of this study is to generate hypotheses about unknown drugs associated with the onset or worsening of Raynaud's Phenomenon (RP) and to explore their potential pathophysiological mechanisms through a mixed disproportionality/clustering analysis from the WHO pharmacovigilance database.
Alex Hlavaty   +4 more
wiley   +1 more source

Mid- to late-life migraine diagnoses and risk of dementia:a national register-based follow-up study [PDF]

open access: yes, 2020
Background: Previous studies found an association between migraine and dementia, which are two leading causes of disability. However, these studies did not differentiate between migraine types and did not investigate all prevalent dementia subtypes.
Andersen, Per Kragh   +8 more
core   +1 more source

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

open access: yesBritish Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander   +5 more
wiley   +1 more source

Neuropsychopharmacology of hallucinogenic and non‐hallucinogenic 5‐HT2A receptor agonists

open access: yesBritish Journal of Pharmacology, EarlyView.
Psychedelic drugs such as LSD and psilocin were once relegated to the fringes of medical research because of their association with counterculture movements and a perceived concern about harm through recreational use, and their consequent legal prohibition in the early 1970s.
Trevor Sharp, Aurelija Ippolito
wiley   +1 more source

Psychedelics, entactogens and psychoplastogens for depression and related disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Economic benefits of treating medication-overuse headache - results from the multicenter COMOESTAS project [PDF]

open access: yes, 2018
Background: Medication-overuse headache is a costly disease for individuals and society. Objective: To estimate the impact of medication-overuse headache treatment on direct and indirect headache-related health care costs. Methods: This prospective
Bendtsen, Lars   +13 more
core   +1 more source

Comprehensive assessment of erenumab efficacy in participants with high‐frequency episodic migraine with at least one previously failed preventive treatment: The EMBRACE study

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To evaluate the effect of erenumab treatment beyond monthly migraine days in patients with high‐frequency episodic migraine who did not respond to at least one previous migraine preventive treatment. Background Reduction in monthly migraine days has been the efficacy standard for migraine preventive treatments; however, it does not ...
Gabriel Paiva da Silva Lima   +11 more
wiley   +1 more source

Migraine-like Headache in a Patient with Complement 1 Inhibitor Deficient Hereditary Angioedema [PDF]

open access: yes, 2012
We report on an angioedema patient with a genetic defect in complement 1 inhibitor, manifesting migraine-like episodes of headache, effective prophylaxis with Danazol, and triptan for a treatment of acute clinical episode.
Agostoni   +16 more
core   +2 more sources

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