Results 21 to 30 of about 1,900 (208)
Migraine-like Headache in a Patient with Complement 1 Inhibitor Deficient Hereditary Angioedema [PDF]
, 2012 We report on an angioedema patient with a genetic defect in complement 1 inhibitor, manifesting migraine-like episodes of headache, effective prophylaxis with Danazol, and triptan for a treatment of acute clinical episode.
Agostoni +16 more
core +2 more sources
Narcotic analgesics for acute migraine in the emergency room: are we meeting headache societies\u27 guidelines? [PDF]
, 2006 We analysed 161 patients with acute migraine in our emergency room (ER) to identify the use of narcotic analgesics as first-line treatment. Twenty-four percent of patients were treated with opioid analgesics and 76% patients were treated with non-opioid ...
Khan, Saqib Uddin +3 more
core +2 more sources
Does the Addition of Ginger Decrease Migraine Pain? [PDF]
, 2020 OBJECTIVE: The objective of this selective EBM review is to determine whether or not “does the addition of ginger decrease migraine pain”. STUDY DESIGN: A systematic review of three peer-reviewed studies published between the years of 2011-2018.
Nguyen, Stephanie
core +1 more source
Sensitization of the Trigeminovascular Pathway: Perspective and Implications to Migraine Pathophysiology [PDF]
, 2012 Migraine headache is commonly associated with signs of exaggerated intracranial and extracranial mechanical sensitivities. Patients exhibiting signs of intracranial hypersensitivity testify that their headache throbs and that mundane physical activities ...
Bernstein, Carolyn A., Burstein, Rami
core +1 more source
Gepants, calcitonin gene-related peptide antagonists, for abortive treatment of migraine: current status [PDF]
, 2021 Migraine is a neurovascular disorder characterized by unilateral, recurrent, pulsating, throbbing, and moderate to severe headache. Triptans use is often limited by their poor efficacy, reports of poor responders, and contraindicated in patients with ...
Gaddam, Soni, Padi, Satyanarayana S. V.
core +2 more sources
ChemMedChem, Accepted Article.We have described the synthesis of a new series of LCAPs (long‐chain arylpiperazine) as serotoninergic ligands (FG 1‐18). The combination of structural elements including heterocyclic nucleus, propyl chain and 4,5‐dihydrothiazol‐2‐ylphenylpiperazines, led to the preparation of different derivatives tested for their affinity toward 5‐HT1A, 5‐HT2A and 5 ...
Giorgia Andreozzi +18 more
wiley +1 more source
Grass-endophytes in plant protection [PDF]
, 2009 Agriculturists have long known that certain grass species infected with systemic fungal endophytes are highly resistant to both vertebrate and invertebrate ...
Saikkonen, Kari
core
British Journal of Pharmacology, EarlyView.Abstract G protein‐coupled receptors (GPCRs) are one of the major drug targets. In recent years, computational drug design for GPCRs has mainly focused on static structures obtained through X‐ray crystallography, cryogenic electron microscopy (cryo‐EM) or in silico modelling as a starting point for virtual screening campaigns. However, GPCRs are highly
Marta Lopez‐Balastegui +6 more
wiley +1 more source
Progress on the development of Class A GPCR‐biased ligands
British Journal of Pharmacology, EarlyView.Class A G protein‐coupled receptors (GPCRs) continue to garner interest for their essential roles in cell signalling and their importance as drug targets. Although numerous drugs in the clinic target these receptors, over 60% GPCRs remain unexploited. Moreover, the adverse effects triggered by the available unbiased GPCR modulators, limit their use and
Paula Morales +20 more
wiley +1 more source
Is Exercise Safe and Effective at Decreasing the Incidence of Tension-Type Headaches? [PDF]
, 2011 OBJECTIVE: To determine whether exercise is safe and effective at lowering the incidence of tension-type ...
Pessolano, Ashley
core +1 more source