Results 51 to 60 of about 5,158 (243)

Migraine and Cardiovascular Disorders [PDF]

open access: yes, 2016
From a clinical point of view, differentiation of numerous forms of migraine depends on the accompanying diseases with prevailing cardiovascular symptoms.
Minchev, D.
core   +2 more sources

Efficacy and safety of rimegepant for the preventive treatment of migraine in Japan: A double‐blind, randomized controlled trial

open access: yesHeadache: The Journal of Head and Face Pain, Volume 65, Issue 8, Page 1403-1412, September 2025.
Plain Language Summary: This study tested the effectiveness of rimegepant for migraine prevention in Japan. Results showed that rimegepant was more effective than placebo in reducing monthly migraine days, with very few adverse effects. These results support the previous findings from a clinical study conducted in the United States and broaden them to ...
Shigekazu Kitamura   +11 more
wiley   +1 more source

Novel 4,5‐Dihydrothiazole‐Phenylpiperazine Derivatives: Synthesis, Docking Studies and Pharmacological Evaluation as Serotonergic Agents

open access: yesChemMedChem, Volume 20, Issue 15, August 2, 2025.
The synthesis of a new series of 4,5‐dihydrothiazol‐2‐ylphenylpiperazine derivatives as serotoninergic ligands is described and tested for their affinity toward 5‐HT1A, 5‐HT2A,and 5‐HT2C and selected for further in vivo assays to determine their functional activity. The pharmacological studies highlight that among the developed derivatives, FG‐7 and FG‐
Giorgia Andreozzi   +18 more
wiley   +1 more source

Assessing Self‐medication Practices Among Healthcare Providers With Migraine in Saudi Arabia

open access: yesBrain and Behavior, Volume 15, Issue 8, August 2025.
ABSTRACT Objectives Migraine is a neurological disorder characterized by recurrent headaches resulting from abnormal regulation of sensory input to the head. Self‐medication (SM) is a prevalent practice among healthcare providers (HCPs), with potentially detrimental consequences.
Bandar Nasser Aljafen   +6 more
wiley   +1 more source

Insights into the Dynamics and Binding Mechanisms of the Alkhumra Virus NS2B/NS3 Protease: A Molecular Dynamics Study

open access: yesAdvanced Theory and Simulations, Volume 8, Issue 7, July 2025.
The ΔRMSF$\Delta {\rm RMSF}$ analysis reveals significant flexibility differences between free NS3 and the NS2B/NS3 complex, with notable deviations in specific regions. Key residues driving NS2B binding are identified, and the protonation state of catalytic serine affects oxyanion hole formation.
Jurica Novak   +2 more
wiley   +1 more source

Migraine: Diagnosis, treatment and understanding c1960-2010 [PDF]

open access: yes, 2014
seminar transcriptThere are around eight million migraine sufferers in the UK today. This Witness Seminar looked at the last 50 years of research into the diagnosis and treatment of the condition and the changing attitudes of the medical profession ...
Overy, C, Tansey, EM
core  

Ergotamine Stimulates Human 5-HT4-Serotonin Receptors and Human H2-Histamine Receptors in the Heart [PDF]

open access: gold, 2023
Hannes Jacob   +7 more
openalex   +1 more source

Over‐the‐Counter Medications for Sinus Headache: A Cross‐Sectional Survey Study

open access: yesOTO Open, Volume 9, Issue 3, July-September 2025.
Abstract Objective Sinus headache is a common complaint that can be due to chronic rhinosinusitis (CRS) or non‐rhinogenic facial pain/pressure (NRFP). The purpose of this study is to characterize over‐the‐counter (OTC) medications used for sinus headache. Study Design Cross‐sectional study. Setting Tertiary care academic center.
Nathan Gabriel Sattah   +6 more
wiley   +1 more source

Percutaneous Closure of Patent Foramen Ovale for the Treatment of Refractory Migraine Headaches [PDF]

open access: yes
Background: Migraine headaches both with and without aura vary in frequency, duration and intensity, affecting the quality of life of up to 10% of the total population. Migraines are treated with both prophylactic and acute medications.
Anderson, Kristina
core   +1 more source

Clinical-Neurological Characteristics of Abuse Headaches in Primary Headaches [PDF]

open access: yes, 2023
This article discusses the origin, clinical and neurological features of abuses headache in primary headaches such as migraine and tension-type headaches, as well as the principles of correct and early diagnosis and prevention of this disease.
Saidvaliyev F.S., Rakhimova Sh.M.
core   +1 more source

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