Results 121 to 130 of about 256,638 (238)
Advanced Science, EarlyView.A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li +9 more
wiley +1 more source
Erosión del pasado y formas de relieve actuales en la montaña cantábrica
Ería, 2017 openaire +2 more sources
, 1965 With an eminently clinical judgment, we can define the cervical erosion as a red spot, which appears in the vicinity of the external os and contrast of pale pink normal portio.Con un criterio eminentemente clínico, podemos definir la erosión cervical ...
González Merlo, Jesús
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Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies
Advanced Science, EarlyView.This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan +5 more
wiley +1 more source
Advanced Science, EarlyView.Lactate accumulation in glioblastoma drives lactylation of STING at lysine 370, a primate‐conserved residue. K370 lactylation weakens STING‐TBK1 binding, destabilizes STING, and disrupts ER‐to‐Golgi trafficking, blunting type I interferon signaling. LDHA inhibition reverses K370 lactylation and improves the antitumor efficacy of STING agonism combined ...
Yueyao Wu +11 more
wiley +1 more source
Mecanismos de corrosión-erosión en aceros inoxidables: influencia de variables hidrodinámicas y de la aplicación de recubrimientos de TIN [PDF]
, 2004 En este trabajo se estudió el efecto de la velocidad y el ángulo medio de impacto sobre el sinergismo entre corrosión y erosión de dos aceros inoxidables, con y sin recubr imiento de nitruro de titanio.
López Ochoa, Diana María
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Advanced Science, EarlyView.A root‐inspired microneedle array patch uses lattice‐based mechanical interlocking to unite rigid microneedles with a flexible substrate. The interlocked rigid–soft architecture improves interfacial bonding, supports stable adhesion on curved and wet tissues under dynamic motion, and provides a versatile platform for robust biointerfacing and future ...
Jongchan Lee +9 more
wiley +1 more source
Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency
Advanced Science, EarlyView.How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen +10 more
wiley +1 more source
Papeles de Geografía, 1999 Se establece, en una primera aproximación, el óptimo de cobertura en función de las pérdidas de suelo por erosión hídrica y de las pérdidas de lluvia por interceptación, en un matorral (romeral), en condiciones ambientales semiáridas mediterráneas, con ...
F. Belmonte Serrato +3 more
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Metodologías sostenibles para el control de la erosión en laderas naturales y taludes artificiales.
, 2012 Se presentan los aspectos fundamentales y principales consideraciones para el tratamiento de taludes erosionados haciendo una descripción de los métodos hasta ahora desarrollados aplicados al control de la erosión.
González, Julián Rodrigo Quintero +1 more
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