Results 151 to 160 of about 252,417 (236)

Computation and Structure‐Guided Arginine Scanning Engineers a Hyperactive AP Endonuclease for Multiplex Viral RNA Sensing

open access: yesAdvanced Science, EarlyView.
Computational and structure‐guided arginine scanning rewires the DNA‐binding interface of APE1 to create APE1‐Evo, a hyperactive yet specific AP endonuclease. Integrated into the NAPTUNE‐V2.0 cascade, APE1‐Evo enables amplification‐free, multiplex viral RNA sensing for dengue virus and influenza A/B, highlighting a general strategy for engineering ...
Junlan Wang   +20 more
wiley   +1 more source

Monitoreo espacio-temporal de la erosión hídrica en la cuenca de la Amazonía ecuatoriana

open access: yesSiembra
La cuenca ecuatoriana del Amazonas, a pesar de su relieve mayormente plano o ligeramente ondulado y su densa cobertura vegetal, enfrenta un riesgo latente de degradación de los suelos debido a la erosión, ocasionada por factores como la deforestación ...
Javier Martín   +4 more
doaj  

Chromatin Packing Domain Engineering Through the Manipulation of Nuclear Cationic States

open access: yesAdvanced Science, EarlyView.
Manipulation of intranuclear divalent cation concentrations rapidly and reversibly remodels chromatin packing domains in living cells. Magnesium depletion disrupts domain compaction, heterochromatin organization, and transcriptional regulation, whereas magnesium loading promotes more compact and stable domains.
Cody L. Dunton   +13 more
wiley   +1 more source

Unveiling Multi-Hazard Hotspots in Kabul: An Integrated Geospatial Assessment in a Data-Scarce Urban Environment. [PDF]

open access: yesEnviron Manage
Rafiee M   +6 more
europepmc   +1 more source

Long‐Chain Molecule Reconstruction of Novel Solvation Structure to Stabilize Zinc Metal Anode

open access: yesAdvanced Science, EarlyView.
Triethylene glycol diacetate (TGD), with unique long‐chain characteristics and rich oxygen‐containing functional groups, was used as an electrolyte additive to reconstruct the solvation structure. TGD can reduce the erosion of H2O molecules on the Zn anode, effectively homogenize the electric field distribution. Therefore, the Zn//Zn symmetric cell can
Changdong Chen   +6 more
wiley   +1 more source

Bistable Networks Enable Complex Shape Changes

open access: yesAdvanced Science, EarlyView.
Transition‐controlled metamaterials are networks of bistable mechanical memory that store local binary states and express them as global shape change. By decoupling low‐force programming from high‐force holding, a single lattice is reconfigured into distinct 2D profiles and 3D surfaces without continuous actuation, enabling reusable morphing materials ...
Sawyer Thomas, Jeffrey Lipton
wiley   +1 more source

Modeling wind erosion susceptibility of Eastern Iran using machine learning. [PDF]

open access: yesPLoS One
Damaneh Javad M   +4 more
europepmc   +1 more source

Beyond Traditional Phenolics: Disulfide Bonds for Performance Enhancement of Aerospace Ablation‐Resistant Materials from Processing to Recycling

open access: yesAdvanced Science, EarlyView.
The dynamic disulfide bonds facilitated the development of high‐performance aerospace ablation‐resistant materials. At moderate temperature, the dissociation and recombination of disulfide bonds ensured excellent processability, mechanical properties, and recycling ability of phenolic resin; at high temperature, cleavage of disulfide bonds produced ...
Yu Li   +9 more
wiley   +1 more source

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