Results 151 to 160 of about 9,851 (308)

Endothelial PDGF Signaling Dysregulation Impairs Testicular Interstitial Homeostasis in Diabetes

Advanced Science, EarlyView.
Testicular endothelial cells (TECs) function as central signaling hubs that coordinate interstitial homeostasis. Diabetes disrupts TEC‐derived PDGF signaling, silences the JUND‐MCL1 survival program in Leydig cells, and impairs peritubular function, leading to fibrosis and testosterone insufficiency.
Wenxiu Zhang, Kai Hong, Yanling Tang, Lina Cui, Xiaojian Lu, Jianxing Cheng, Yangyi Fang, Qiaoling Jiang, Ziyan Zhuang, Songzhan Gao, Hui Jiang, Qiang Liu, Jingtao Guo, Zhe Zhang, Xiaoyan Wang   +14 more
wiley   +1 more source

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

Advanced Science, EarlyView.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang, Yujiao He, Pei Zou, Xiaoyi Wang, Gang Peng, Xiangying Deng   +5 more
wiley   +1 more source

Scaling effect for estimating soil loss in the RUSLE model using remotely sensed geospatial data in Korea

, 2006
International audienceAccurate estimation of soil loss/deposition forced by rainfall events plays a major role in water resources management and it directly affects the quality of agricultural land and water storage capacity in reservoirs. In this paper,
Lee, G.-S., Lee, K.-H.
core   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

Estimating soil erosion utilizing geospatial method and revised universal soil loss equation (RUSLE) of Abu Ghraibat Watershed, Eastern Misan Governorate, Iraq. [PDF]

Sci Rep
Maaroof BF, Kareem HH, Al-Zubaydi JH, Al-Ansari N, Aziz MA, Al-Quraishy DAA, Al-Hasani B, Abdellatif M, Carnacina I, Thannoun RG, Al-Kubaisi MS, Al-Maarofi SS.   +11 more
europepmc   +1 more source

Assessment of soil erosion hazard and its relation to land use land cover changes: Case study from alage watershed, central Rift Valley of Ethiopia. [PDF]

Heliyon, 2023
Taye G, Teklesilassie T, Teka D, Kassa H.   +3 more
europepmc   +1 more source

Asymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections

Advanced Science, EarlyView.
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li, Shike Zhang, Jinggong Liu, Xin Wang, Heng Wang, Hongcan Yang, Yuhao Zhou, Wen Liu, Hongxing Liu, Wenqi Wu   +9 more
wiley   +1 more source

ROS‐Responsive Wedelolactone Hydrogel Promotes Intervertebral Disc Repair by Disrupting the NF‐κB–LCN2 Inflammatory Feedback Loop

Advanced Science, EarlyView.
A mechanically robust, ROS‐responsive hydrogel is engineered to treat intervertebral disc degeneration by targeting the NF‐κB–LCN2 inflammatory feedback loop. By delivering wedelolactone specifically within oxidative niches, this system disrupts macrophage–disc cell crosstalk.
Zimei Wu, Yan Xu, Lang Qin, Zemin Ling, Yingjie Mai, Xiong Tian Guo, Jiajia Chen, Leping Yan, Lin Wang, Liming Bian, Fuxin Wei   +10 more
wiley   +1 more source

Integrating RUSLE, AHP, GIS, and cloud-based geospatial analysis for soil erosion assessment under mediterranean conditions. [PDF]

Sci Rep
Fadl ME, Zekari M, Labad R, Faqeih KY, Abou El-Fadl DM, Zahra WR, Mansour MMA, Rebouh NY, Kucher DE, Poddubsky A, Elnagar AS, Ali EA.   +11 more
europepmc   +1 more source

Forces Driving Change in Rwandan Smallholder Agriculture 1990-2001 [PDF]

Food Security Research Project (FSRP) and Division of Agricultural Statistics (DSA) Ministry of Agriculture, Livestock and Forestry MINAGRIfood security, food policy, Rwanda, smallholder agriculture, Crop Production/Industries, Q18,
Donovan, Cynthia, Loveridge, Scott, Mpyisi, Edson   +2 more
core   +1 more source