Results 111 to 120 of about 2,449 (274)
Entwicklungslinien der Betriebswirtschaftslehre von Organisationen „not-for-profit“ [PDF]
, 2018 Die Betriebswirtschaftslehre im deutschsprachigen Raum hat sich, ähnlich wie die nord-amerikanische Managementlehre, stets nur am Rande mit den Besonderheiten der Führung und Steuerung von nicht-erwerbswirtschaftlichen Organisationen befasst: Vereine ...
Gmür, Markus
core
The ERPF Theory and the UCEC Turbine: A New Paradigm for Ocean Energy Conversion
This article introduces the Energy Restoration by Planetary Fields (ERPF) theory, proposing a new paradigm for energy conversion in oceanic flows. Unlike classical models, which consider as available only the kinetic energy associated with the intercepted sectional area—bounded, for example, by the Betz limit—ERPF treats the ocean as an open, dynamic ...
openaire +1 more source
Artificial Organs, EarlyView.Graphical summary of the experimental comparison of shear‐induced hemolysis in pediatric and adult blood using a Couette shearing device. Pediatric blood shows a trend toward lower increase in hemolysis at higher shear stress amplitudes, while no relevant differences are observed at low and intermediate stresses.
Vera Froese +4 more
wiley +1 more source
Performing PET/CT studies: do they create anxiety? [PDF]
, 2014 Introduction: Anxiety is a common problem in primary care and specialty medical settings. Treating an anxious patient takes more time and adds stress to staff.
Abreu, Carla +2 more
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Annals of Public and Cooperative Economics, EarlyView.Abstract An important debate in the field of strategy and industrial organization economics has long focused on whether the industry environment or firm idiosyncrasies have a greater impact on firm performance. However, cooperatives have been excluded from this inquiry, despite profits being the primary means to achieve their social objectives.
Pablo Doucet, Marta Solórzano‐García
wiley +1 more source
British Journal of Haematology, EarlyView.Summary Evidence for an association between insulin‐like growth factors (IGF) and multiple myeloma (MM) is inconsistent. We examined total IGF‐I concentrations and risk of MM by combining baseline serological data among UK Biobank participants (n = 444 187; 732 incident MM) with a two‐sample Mendelian randomisation (MR) analysis using identified ...
Yolanda Benavente +56 more
wiley +1 more source
Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice
Brain Pathology, EarlyView.We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga +11 more
wiley +1 more source
Brain Pathology, EarlyView.A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña +20 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Inhibitors of insulin‐degrading enzyme boost PI cytotoxicity through an increased sensitivity of proteasome to PI inhibitors, induction of ISR, DNA damage and Myc down‐regulation. They overcome PI resistance in vitro and induce tumour regression in vivo.
Laetitia Lesire +28 more
wiley +1 more source
Terrain Synthesis and Authoring based on Iso‐Contours
Computer Graphics Forum, EarlyView.Abstract Digital terrains are central to realistic landscape depiction, yet authoring tools must balance perceptual realism with intuitive artistic control. We propose a compact vector‐based representation that models terrain as nested iso‐contours, inspired by geomorphology and cartography.
B. Huftier +5 more
wiley +1 more source