Results 71 to 80 of about 12,027 (259)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Blockwise Repeated Burst Error Correcting Linear Codes

Ratio Mathematica, 2010
This paper presents a lower and an upper bound on the number of parity check digits required for a linear code that corrects a single sub-block containing errors which are in the form of 2-repeated bursts of length b or less. An illustration of such kind
B.K. Dass, Surbhi Madan
doaj  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Perfect Codes over Non-Prime Power Alphabets: An Approach Based on Diophantine Equations

Mathematics
Perfect error-correcting codes allow for an optimal transmission of information while guaranteeing error correction. For this reason, proving their existence has been a classical problem in both pure mathematics and information theory.
Pedro-José Cazorla García
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Error correcting codes and heterotic Narain CFTs

Journal of High Energy Physics
We study error correcting codes that construct the Narain lattices of heterotic strings as code lattices. We identify, in both E 8 × E 8 and Spin(32)/ℤ2 heterotic strings, a pair of a binary code and a set of the corresponding metric, B field, and ...
Shun’ya Mizoguchi, Takumi Oikawa
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Efficiently stable presentations from error-correcting codes

Discrete Analysis
This paper brings together a wide variety of interesting concepts, in order to rederive a result that formed a key step in the proof of the famous result that MIP${\mathstrut}^*$=RE by Zhengfeng Ji, Anand Natarajan, Thomas Vidick, John Wright, and Henry ...
Michael Chapman, Thomas Vidick, Henry Yuen   +2 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Group Homomorphisms as Error Correcting Codes [PDF]

The Electronic Journal of Combinatorics, 2015
We investigate the minimum distance of the error correcting code formed by the homomorphisms between two finite groups $G$ and $H$. We prove some general structural results on how the distance behaves with respect to natural group operations, such as passing to subgroups and quotients, and taking products.
openaire   +5 more sources