Results 121 to 130 of about 31,673,086 (385)

An Error Analysis of the Geometric Baade-Wesselink Method

, 2003
We derive an analytic solution for the minimization problem in the geometric Baade-Wesselink method. This solution allows deriving the distance and mean radius of a pulsating star by fitting its velocity curve and angular diameter measured ...
Bersier D., Bersier D., Claret A., Dimitar D. Sasselov, Feast M. W., Fernley J., Laney C. D., Margarita Karovska, Massimo Marengo, Mayly Sanchez, Meylan G., Ripepi V., Wesselink A.   +12 more
core   +2 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Research on Pose Error Modeling and Compensation of Posture Adjustment Mechanism Based on WOA-RBF Neural Network

Machines
This paper is aimed to address the issue of decreased accuracy in the ship block docking caused by the structural errors of posture adjustment mechanism.
Hongyu Shen, Honggen Zhou, Yiyang Jin, Lei Li, Bo Deng, Jiawei Xu   +5 more
doaj   +1 more source

3D Particle Tracking Velocimetry Method: Advances and Error Analysis [PDF]

, 2005
A full three-dimensional particle tracking system was developed and tested. By using three separate CCDs placed at the vertices of an equilateral triangle, the threedimensional location of particles can be determined.
Dabiri, D., Hornung, H. G., Mouton, C. A., Ponchaut, N. F.   +3 more
core  

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

Molecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo, Carlos M. Martínez‐Cáceres, Manuel Bernabé‐García, Vicente Munitiz, David Ruiz de Angulo, Pascual Parrilla, Ángeles Ortiz, Luisa F. Martínez de Haro, María L. Cayuela   +8 more
wiley   +1 more source

Fabrication Error Modeling and Analysis of an E-Band MHMIC Balanced Power Detector

IEEE Access
This study models and analyses the fabrication errors of an ultra-wideband (UWB) Schottky diode power detector using miniature hybrid-microwave integrated-circuit (MHMIC) technology.
Mehrdad Harifi-Mood, Nima Souzandeh, Peyman PourMohammadi, Djilali Hammou, Bryan Hosein, Sonia Aissa, Serioja Ovidiu Tatu   +6 more
doaj   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Kantorovich-Stancu type (α,λ,s) - Bernstein operators and their approximation properties

Mathematical and Computer Modelling of Dynamical Systems
In this study, we establish a new class of Kantorovich-Stancu type [Formula: see text]Bernstein operators via an adaptation of Bézier bases which are formulated with the inclusion of the shape parameters [Formula: see text], [Formula: see text], and a ...
Nezihe Turhan, Faruk Özger, Mohammad Mursaleen   +2 more
doaj   +1 more source