Results 141 to 150 of about 31,673,086 (385)

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

High-order numerical method for the fractional Korteweg-de Vries equation using the discontinuous Galerkin method

open access: yesAIMS Mathematics
The fractional Korteweg-de Vries (KdV) equation generalizes the classical KdV equation by incorporating truncation effects within bounded domains, offering a flexible framework for modeling complex phenomena.
Yanhua Gu
doaj   +1 more source

Backward error analysis for multisymplectic discretizations of Hamiltonian PDEs

open access: yes, 2004
Several recently developed multisymplectic schemes for Hamiltonian PDEs have been shown to preserve associated local conservation laws and constraints very well in long time numerical simulations.
Islas, Alvaro L., Schober, Constance M.
core   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Some Methodological Guidelines for Contrastive Analysis and Error Analysis

open access: yesJournal of Modern Languages, 2017
This article offers some guidelines in the methods used and the steps to follow in conducting research in contrastive analysis (CA) and error analysis (EA).
Kim Yok Choi
doaj  

Error analysis of bit-flip qubits under random telegraph noise for low and high temperature measurement application

open access: yes, 2020
Achieving small error for qubit gate operations under random telegraph noise (RTN) is of great interest for potential applications in quantum computing and quantum error correction.
Prabhakar, Sanjay
core  

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

open access: yesMolecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva   +5 more
wiley   +1 more source

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