Results 21 to 30 of about 7,378,106 (231)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Error Analysis on Essay Writing Organization [PDF]

open access: yes, 2016
This research is designed to analyze students' error on essay writing organization. The writers focus on the one category of error identifications that is organization.
Apandi, A. (Apandi)   +1 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Average Error Probability Analysis in mmWave Cellular Networks

open access: yes, 2015
In this paper, a mathematical framework for the analysis of average symbol error probability (ASEP) in millimeter wave (mmWave) cellular networks with Poisson Point Process (PPP) distributed base stations (BSs) is developed using tools from stochastic ...
Gursoy, M. Cenk, Turgut, Esma
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Error Analysis of Phonetic Fossilization Uttered by English Department Students University of PGRI Semarang [PDF]

open access: yes, 2016
Penelitian ini bertujuan untuk menentukan tipe dan latar belakang fosilisasi fonetik yang diucapkan oleh mahasiswa semester 5 Pendidikan Bahasa Inggris di Universitas PGRI Semarang tahun 2014/2015.
Ardini, S. N. (Sukma)   +2 more
core   +2 more sources

Analysis of quantum error correction with symmetric hypergraph states

open access: yes, 2018
Graph states have been used to construct quantum error correction codes for independent errors. Hypergraph states generalize graph states, and symmetric hypergraph states have been shown to allow for the correction of correlated errors. In this paper, it
Bruß, Dagmar   +2 more
core   +1 more source

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