Results 71 to 80 of about 6,085,361 (298)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Characterizing coherent errors using matrix-element amplification

npj Quantum Information
Repeating a gate sequence multiple times amplifies systematic errors coherently, making it a useful tool for characterizing quantum gates. However, the precision of such an approach is limited by low-frequency noises, while its efficiency hindered by time-consuming scans required to match up the phases of the off-diagonal matrix elements being ...
Jonathan A. Gross, Élie Genois, Dripto M. Debroy, Yaxing Zhang, Wojciech Mruczkiewicz, Ze-Pei Cian, Zhang Jiang   +6 more
openaire   +3 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Tensor network noise characterization for near-term quantum computers

Physical Review Research
Characterization of noise in current near-term quantum devices is of paramount importance to fully use their computational power. However, direct quantum process tomography becomes unfeasible for systems composed of tens of qubits.
Stefano Mangini, Marco Cattaneo, Daniel Cavalcanti, Sergei Filippov, Matteo A. C. Rossi, Guillermo García-Pérez   +5 more
doaj   +1 more source

Estimation and validation of elastic constants in fused filament fabrication 3D printing: From mesoscale to macroscale

Materials & Design
Evaluating the mechanical properties of 3D-printed parts is a cumbersome task. This study poses an approach based on computational homogenization to estimate the elastic constants of fused filament fabrication 3D-printed parts.
A. Arias-Blanco, M. Álvarez-Blanco, R. Belda, M. Marco   +3 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Efficient characterization of correlated SPAM errors

, 2018
State preparation and measurement (SPAM) errors limit the performance of many gate-based quantum computing architecures, but are partly correctable after a calibration step that requires, for an exact implementation on a register of $n$ qubits, $2^n$ additional characterization experiments, as well as classical post-processing.
Sun, Mingyu, Geller, Michael R.
openaire   +2 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Multiclass Classification of Hepatic Anomalies with Dielectric Properties: From Phantom Materials to Rat Hepatic Tissues

Sensors, 2020
Open-ended coaxial probes can be used as tissue characterization devices. However, the technique suffers from a high error rate. To improve this technology, there is a need to decrease the measurement error which is reported to be more than 30% for an in
Tuba Yilmaz
doaj   +1 more source

Error characterization in quantum information processing: A protocol for analyzing spatial correlations and its experimental implementation [PDF]

, 2008
We present a protocol for error characterization and its experimental implementation with four qubits in liquid state NMR. The method is designed to retrieve information about spatial correlations and scales as $O({n}^{w})$, where $w$ is the maximum ...
C. C. López, Benjamin Lévi, David G. Cory   +2 more
semanticscholar   +1 more source