Results 141 to 150 of about 659,747 (309)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Determinants of timber exports in Nigeria: an error correction modeling approach [PDF]

This study analyzed the factors influencing the exports of timber in Nigeria with the aid of Error Correction Model (ECM) representation procedures. The analysis was carried out with the data collected on roundwood and sawnwood over 33 years (1970 – 2003)
Yusuf, Adesina Sulaiman, Edom, Cyprian .O   +1 more
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

SPARC tokamak error field expectations and physics-based correction coil design

Nuclear Fusion
Non-axisymmetric magnetic field coils have been designed to provide efficient error field (EF) correction and suppress edge localized modes in SPARC—a compact high-field tokamak that is presently under construction at Commonwealth Fusion Systems.
N.C. Logan, C.E. Myers, R. Sweeney, C. Paz-Soldan, M. Pharr, N. Leuthold, M. Nickerson, J. Halpern, I. Stewart   +8 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Effects of Macroeconomic Variables on Stock Prices in Malaysia: An Approach of Error Correction Model [PDF]

This paper attempts to examine the short-run and long-run causal relationship between Kuala Lumpur Composite Index (KLCI) and selected macroeconomic variables namely inflation, money supply and nominal effective exchange rate during the pre and post ...
Fouad, Md., Rohilina, Wisam, Asmy, Mohamed, Hassama, Aris   +3 more
core   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

How error correction affects polymerase chain reaction deduplication: A survey based on unique molecular identifier datasets of short reads

Quantitative Biology
Next‐generation sequencing data are widely utilised for various downstream applications in bioinformatics and numerous techniques have been developed for PCR‐deduplication and error‐correction to eliminate bias and errors introduced during the sequencing.
Pengyao Ping, Tian Lan, Shuquan Su, Wei Liu, Jinyan Li   +4 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Comparison of state-of-the-art error-correction coding for sequence-based DNA data storage. [PDF]

Nat Commun
Gimpel AL, Remschak A, Stark WJ, Heckel R, Grass RN.   +4 more
europepmc   +3 more sources