Results 41 to 50 of about 556,020 (262)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Decoding Quantum Error Correction Codes With Local Variation

open access: yesIEEE Transactions on Quantum Engineering, 2020
In this article, we investigate the role of local information in the decoding of the repetition and surface error correction codes for the protection of quantum states.
Michael Hanks   +2 more
doaj   +1 more source

Low-Latency Burst Error Detection and Correction in Decision-Feedback Equalization

open access: yesIEEE Open Journal of Circuits and Systems, 2021
This article describes low latency, zero overhead DFE burst error correction technique. Without any encoder or decoder latency, the proposed technique makes use of the existing pre-cursor ISI to detect and correct errors on a burst of data.
Shovon Dey, Aurangozeb, Masum Hossain
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Thermodynamics of Error Correction

open access: yesPhysical Review X, 2015
Information processing at the molecular scale is limited by thermal fluctuations. This can cause undesired consequences in copying information since thermal noise can lead to errors that can compromise the functionality of the copy.
Pablo Sartori, Simone Pigolotti
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Error Correction for Semi-Supervised Classification Based on Fix Match [PDF]

open access: yesITM Web of Conferences
Semi-supervised learning (SSL) leverages unlabeled data to support model training, thereby improving model accuracy. However, most existing SSL methods rely heavily on unlabeled data for model correction while often overlooking the potential error ...
Zhang Ziqian
doaj   +1 more source

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