Results 41 to 50 of about 1,470,732 (345)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Current Prediction Error Reduction Method of Predictive Current Control for Permanent Magnet Synchronous Motors

open access: yesIEEE Access, 2020
Predictive current control (PCC) has been widely investigated in motor drive field. The PCC is a model-based control method and the motor prediction model is quite sensitive to motor parameters which may be inaccurately measured and change under ...
Feng Niu   +6 more
doaj   +1 more source

Lexical Speaker Error Correction: Leveraging Language Models for Speaker Diarization Error Correction

open access: yesINTERSPEECH 2023, 2023
Speaker diarization (SD) is typically used with an automatic speech recognition (ASR) system to ascribe speaker labels to recognized words. The conventional approach reconciles outputs from independently optimized ASR and SD systems, where the SD system typically uses only acoustic information to identify the speakers in the audio stream. This approach
Paturi, Rohit   +2 more
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Pronunciation Guided Copy And Correction Model For ASR Error Correction

open access: yesInternational Journal of Machine Learning and Cybernetics, 2023
Abstract Error correction has been proven an effective means of refining mistakes produced by the Automatic Speech Recognition (ASR) models, thereby contributing to a notable reduction in the word error rate (WER) at ASR post-edit stage. Existing ASR error correction methods built upon sequence-to-sequence architecture may suffer from the over ...
Ling Dong   +5 more
openaire   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Machine Learning for Model Error Inference and Correction

open access: yesJournal of Advances in Modeling Earth Systems, 2020
Model error is one of the main obstacles to improved accuracy and reliability in numerical weather prediction (NWP) and climate prediction conducted with state‐of‐the‐art, comprehensive high‐resolution general circulation models.
Massimo Bonavita, Patrick Laloyaux
doaj   +1 more source

Using error correction to determine the noise model

open access: yes, 2007
Quantum error correcting codes have been shown to have the ability of making quantum information resilient against noise. Here we show that we can use quantum error correcting codes as diagnostics to characterise noise. The experiment is based on a three-
Damien Simon   +11 more
core   +1 more source

Correction of Model Reduction Errors in Simulations [PDF]

open access: yesSIAM Journal on Scientific Computing, 2018
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Lipponen, A.   +4 more
openaire   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

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