Results 201 to 210 of about 133,952 (267)

Gray matter volume and structural covariance alterations in young males with childhood-onset growth hormone deficiency. [PDF]

open access: yesBMC Med Imaging
Wang S   +10 more
europepmc   +1 more source

Deucravacitinib in Active Psoriatic Arthritis: Efficacy and Safety up to 52 Weeks From the Randomized, Double‐Blind, Phase 3 POETYK PsA‐2 Trial

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To assess the efficacy and safety of deucravacitinib, an oral, selective tyrosine kinase 2 inhibitor, in patients with psoriatic arthritis (PsA) who were naive to biologic disease‐modifying antirheumatic drugs or received tumor necrosis factor inhibitors. Methods In the 52‐week (W), double‐blind, placebo‐controlled, phase 3 POETYK PsA‐2 study
Philip J. Mease   +20 more
wiley   +1 more source

Cortical Network Overconnectivity Relates to Sensory, Cognitive, and Social Dimensions in Young Children With Autism Spectrum Disorder

open access: yesAutism Research, EarlyView.
ABSTRACT The heterogeneity in both the neurobiological mechanisms and the phenotypic presentations of autism spectrum disorder (ASD) poses a major challenge to clinical and translational research. Alterations in functional connectivity (FC) have been associated with ASD, yet it remains unclear whether and how divergent brain network properties may ...
Borja Rodríguez‐Herreros   +16 more
wiley   +1 more source

‘They Even Have the Capacity, but the Places Aren't Prepared to Receive Them’: Community Environment and Participation of Autistic Children in a Family‐Engaged Research Analysis

open access: yesAutism Research, EarlyView.
ABSTRACT To examine the associations between community environmental barriers and support and the participation of autistic children, and to interpret these findings from the perspective of caregivers engaged as research partners. This cross‐sectional observational study employed a mixed‐methods design.
Léia Cordeiro de Oliveira   +7 more
wiley   +1 more source

FEMA-Long: Modeling unstructured covariances for discovery of time-dependent effects in large-scale longitudinal datasets. [PDF]

open access: yesPLoS Genet
Parekh P   +25 more
europepmc   +1 more source

Counting, Cardinality and Conservation in Autistic Children

open access: yesAutism Research, EarlyView.
ABSTRACT This study examined the understanding of cardinality and conservation in children with and without autism (aged 4–7 years, without intellectual disability), and its relation to counting strategies. A total of 82 children participated in the study, including 41 autistic children (36 boys, 5 girls) and 41 age‐ and sex‐matched non‐autistic peers.
Irene Polo‐Blanco   +2 more
wiley   +1 more source

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva   +8 more
wiley   +1 more source

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