Results 71 to 80 of about 2,569,797 (292)

Quantum Detection with Unknown States

open access: yes, 2005
We address the problem of distinguishing among a finite collection of quantum states, when the states are not entirely known. For completely specified states, necessary and sufficient conditions on a quantum measurement minimizing the probability of a ...
A. Ben-Tal   +12 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Principles of error detection and error correction codes [PDF]

open access: yes, 1971
Report is reviewed which considers theoretical basis of groups, rings, fields, and vector spaces, and their relationship to algebraic coding theory.
Perlman, M.
core   +1 more source

State selective detection of hyperfine qubits

open access: yes, 2014
In order to faithfully detect the state of an individual two-state quantum system (qubit) realized using, for example, a trapped ion or atom, state selective scattering of resonance fluorescence is well established.
Piltz, Christian   +3 more
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Optimising Solar Power Plant Reliability Using Neural Networks for Fault Detection and Diagnosis

open access: yesElektronika ir Elektrotechnika
This study introduces an intelligent method to monitor grid-connected solar power stations, focussing on detecting problems in their energy output through the use of artificial neural networks (ANN).
Mohammed Bouzidi   +3 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Remote Control Device for the Detection and Correction of Errors in the FDM 3D Printing Process in Real Time

open access: yesEngineering Proceedings
This project focuses on developing a remote control device for the real-time detection and correction of errors in fused deposition modeling (FDM) 3D printing.
Henry Requena   +3 more
doaj   +1 more source

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