Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
SumVg: Total Heritability Explained by All Variants in Genome-Wide Association Studies Based on Summary Statistics with Standard Error Estimates. [PDF]
So HC, Xue X, Ma Z, Sham PC.
europepmc +1 more source
Local error estimates for adaptive simulation of the Reaction-Diffusion Master Equation via operator splitting. [PDF]
Hellander A +3 more
europepmc +1 more source
Propagation of Blood Function Errors to the Estimates of Kinetic Parameters with Dynamic PET [PDF]
Yafang Cheng, İmam Şamil Yetik
openalex +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Error estimates for the analysis of differential expression from RNA-seq count data. [PDF]
Burden CJ, Qureshi SE, Wilson SR.
europepmc +1 more source
A posteriori error estimates for the Laplace-Beltrami operator on\n parametric $C^2$ surfaces [PDF]
Andrea Bonito, Alan Demlow
openalex +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Approximation of eigenvalues for unbounded Jacobi matrices using finite submatrices
Monvel Anne, Zielinski Lech
doaj +1 more source
Microfluidic electro‐viscoelastic manipulation of extracellular vesicles
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh +7 more
wiley +1 more source

