FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Constraints on error rate revealed by computational study of G•U tautomerization in translation. [PDF]
Nucleic Acids Res, 2021 Kazantsev A, Ignatova Z.
europepmc +1 more source
Small sample statistics for classification error rates I : error rate measurements
, 1995 Several methods (independent subsamples, leave-one-out, cross-validation, and bootstrapping) have been proposed for estimating the error rates of classifiers. The rationale behind the various estimators and the causes ofthe sometimes conflicting claims regarding their bias and precision are explored in this paper.
Martin, J. Kent, Hirschberg, D. S.
openaire +2 more sources
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Divergence-degenerate spatial multiplexing towards future ultrahigh capacity, low error-rate optical communications. [PDF]
Light Sci Appl, 2022 Wan Z +5 more
europepmc +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Forensic science and the principle of excluded middle: "Inconclusive" decisions and the structure of error rate studies. [PDF]
Forensic Sci Int Synerg, 2021 Biedermann A, Kotsoglou KN.
europepmc +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Shift Volume Directly Impacts Neuroradiology Error Rate at a Large Academic Medical Center: The Case for Volume Limits. [PDF]
AJNR Am J NeuroradiolIvanovic V +6 more
europepmc +2 more sources
Electronic monitoring of doffing using video surveillance to minimise error rate and increase safety at Howard Springs International Quarantine Facility. [PDF]
Antimicrob Resist Infect Control, 2022 Curtis SJ +6 more
europepmc +1 more source