Results 111 to 120 of about 1,529,727 (337)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Goldmann tonometry tear film error and partial correction with a shaped applanation surface

Clinical Ophthalmology, 2018
Sean J McCafferty,1–4 Eniko T Enikov,5 Jim Schwiegerling,2,3 Sean M Ashley1,3 1Intuor Technologies, 2Department of Ophthalmology, University of Arizona College of Medicine, 3University of Arizona College of Optical Science, 4Arizona Eye ...
McCafferty SJ, Enikov ET, Schwiegerling J, Ashley SM   +3 more
doaj  

Palate-referenced Articulatory Features for Acoustic-to-Articulator Inversion [PDF]

, 2014
The selection of effective articulatory features is an important component of tasks such as acoustic-to-articulator inversion and articulatory synthesis.
Berry, Jeffrey J., Ji, An, Johnson, Michael T   +2 more
core   +1 more source

Bivalent separation into univalents precedes age-related meiosis I errors in oocytes [PDF]

, 2015
Yogo Sakakibara, Shu Hashimoto, Yoshiharu Nakaoka, Anna Kouznetsova, Christer Höög, Tomoya S. Kitajima   +5 more
openalex   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

A Research on a Method of Error Separation Based on Wavelet Analysis [PDF]

, 2013
Gang Yao, Jianjun Zhao, Deyi Sang
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Development of novel computational models based on artificial intelligence technique to predict liquids mixtures separation via vacuum membrane distillation

Scientific Reports
The fundamental objective of this paper is to use Machine Learning (ML) methods for building models on temperature (T) prediction using input features r and z for a membrane separation process.
Yanfen Wei
doaj   +1 more source

Separation and compensation of nonlinear errors in sub-nanometer grating interferometers

, 2022
Qilin Zeng, Zhengyi Zhao, Hao Du, Xianming Xiong, Wentao Zhang, Peng Wang, Zhicheng Zhang, Yunfeng Guo   +7 more
openalex   +1 more source

A new sub-nanometre error separation technique

, 2020
The accuracy of roundness measurement is limited by the repeatability of measurement machines. For commercial roundness measurement machines, this limitation can be reduced by means of complex solutions to control the parameters' influence and thus limit the non-repeatable effects.
Toguem, Saint-Clair, Vissiere, Alain, Mehdi-Souzani, Charyar, Damak, Mohamed, Anwer, Nabil, Nouira, Hichem   +5 more
openaire   +1 more source