Results 51 to 60 of about 1,050,910 (295)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Low-Rank Separated Representation Surrogates of High-Dimensional Stochastic Functions: Application in Bayesian Inference

, 2013
This study introduces a non-intrusive approach in the context of low-rank separated representation to construct a surrogate of high-dimensional stochastic functions, e.g., PDEs/ODEs, in order to decrease the computational cost of Markov Chain Monte Carlo
Validi, AbdoulAhad
core   +1 more source

All-optical phase regeneration with record PSA extinction ratio in a low-birefringence silicon germanium waveguide [PDF]

, 2016
We report a low-power continuous wave-pumped phase sensitive amplifier (PSA)-based phase regenerator implemented in a passive silicon-based waveguide. A polarization assisted-PSA, consisting of two orthogonally-polarized pumps and a phase-locked signal ...
Bogris, Adonis, Bottrill, Kyle, Brun, Mickael, Ettabib, Mohamed, Hammani, Kamal, Kapsalis, Alexandros, Labeye, Pierre, Nicoletti, Sergio, Parmigiani, Francesca, Petropoulos, Periklis, Richardson, David, Syvridis, Dimitris   +11 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Efficient frequency-domain channel equalisation methods for OFDM visible light communications [PDF]

, 2016
The authors present efficient frequency-domain channel estimation methods based on the intra-symbol frequency-domain averaging (ISFA), minimum mean squared error (MMSE) and weighted inter-frame averaging (WIFA) schemes for the orthogonal frequency ...
Ghassemlooy, Zabih, Li, Hui, Li, Yiwei, Lin, Bangjiang, Tang, Xuan, Wu, Yi, Zhang, Shihao   +6 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

An improved method of direct torque control of induction motor

Gong-kuang zidonghua, 2014
In view of shortcomings of traditional direct torque control method of induction motor that torque and flux linkage have large pulsation and switching frequency is unfixed, the paper put forward an improved direct torque control method with space vector ...
LU Bingjuan, JI Xuande, GE Yunwang
doaj   +1 more source

Low-Dose Image-Guided Pediatric CNS Radiation Therapy: Final Analysis From a Prospective Low-Dose Cone-Beam CT Protocol From a Multinational Pediatrics Consortium

Technology in Cancer Research & Treatment, 2020
Background: Lower-dose cone-beam computed tomography protocols for image-guided radiotherapy may permit target localization while minimizing radiation exposure.
Sara R. Alcorn MD, MPH, PhD, Xian Chiong Zhou MS, Casey Bojechko PhD, Rodrigo A. Rubo BS, Michael J. Chen MD, Karin Dieckmann MD, Ralph P. Ermoian MD, Eric C. Ford PhD, Daria Kobyzeva MD, Shannon M. MacDonald MD, Todd R. McNutt PhD, Alexey Nechesnyuk MD, Kristina Nilsson MD, PhD, Hakan Sjostrand BS, Koren S. Smith MS, Markus Stock PhD, Erik J. Tryggestad PhD, Rosangela C. Villar MD, Brian A. Winey PhD, Stephanie A. Terezakis MD   +19 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Research on integrated communication and positioning technology based on visible light

Dianxin kexue, 2023
Visible light wireless technology transmits information through visible light, utilizing light-emitting diode (LED) light sources to achieve communication and positioning while illuminating.Visible light communication positioning integration (VLCP ...
Wei WANG, Jianping WANG, Lifang FENG, Jianli JIN   +3 more
doaj   +2 more sources