Results 141 to 150 of about 621,842 (299)

A note on the estimation of linear regression models with Heteroskedastic measurement errors [PDF]

open access: yes
I consider the estimation of linear regression models when the independent variables are measured with errors whose variances differ across observations, a situation that arises, for example, when the explanatory variables in a regression model are ...
Daniel G. Sullivan
core  

Strong convergence for weighted sums of (α, β)-mixing random variables and application to simple linear EV regression model

open access: yesOpen Mathematics
In this article, the complete convergence and the Kolmogorov strong law of large numbers for weighted sums of (α,β)\left(\alpha ,\beta )-mixing random variables are presented.
Hu Wenjing, Wang Wei, Wu Yi
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Nonparametric identification and estimation of nonclassical errors-in-variables models without additional information [PDF]

open access: yes
This paper considers identification and estimation of a nonparametric regression model with an unobserved discrete covariate. The sample consists of a dependent variable and a set of covariates, one of which is discrete and arbitrarily correlates with ...
Arthur Lewbel, Xiaohong Chen, Yingyao Hu
core  

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Dynamic Error-in-variables Models

open access: yesAustrian Journal of Statistics, 2016
Several environmental problems are described by models defined by systems of first order differential equations. Typically, the derivatives of concentrations are expressed as functions of independent variables such as temperature, pressure, pH, etc. However, the independent variables are generally known only through measurements made at discrete times.
openaire   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Heterogeneous Income Profiles and Life-Cycle Bias in Intergenerational Mobility Estimation [PDF]

open access: yes
Research on intergenerational income mobility is based on current income since data on lifetime income are typically not available for two generations.
Nybom, Martin, Stuhler, Jan
core  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

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