Results 51 to 60 of about 1,735,832 (325)

Predicting the Future Burden of Renal Replacement Therapy in Türkiye Using National Registry Data and Comparative Modeling Approaches

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is steadily increasing. Türkiye has experienced a similar rise in both the incidence and prevalence of renal replacement therapy over the past decades; however, national‐level projections of future ...
Arzu Akgül, Neriman Sıla Koç, Berrak Itır Aylı   +2 more
wiley   +1 more source

Unbiased Instrumental Variables Estimation Under Known First-Stage Sign [PDF]

, 2015
We derive mean-unbiased estimators for the structural parameter in instrumental variables models with a single endogenous regressor where the sign of one or more first stage coefficients is known.
Andrews, Isaiah, Armstrong, Timothy B.
core   +8 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Accuracy gains from conservative forecasting: Tests using variations of 19 econometric models to predict 154 elections in 10 countries. [PDF]

PLoS ONE, 2019
PROBLEM:Do conservative econometric models that comply with the Golden Rule of Forecasting provide more accurate forecasts? METHODS:To test the effects of forecast accuracy, we applied three evidence-based guidelines to 19 published regression models ...
Andreas Graefe, Kesten C Green, J Scott Armstrong   +2 more
doaj   +1 more source

Bayesian D‐optimal designs for error‐in‐variables models [PDF]

Applied Stochastic Models in Business and Industry, 2017
Bayesian optimality criteria provide a robust design strategy to parameter misspecification. We develop an approximate design theory for Bayesian D‐optimality for nonlinear regression models with covariates subject to measurement errors. Both maximum likelihood and least squares estimation are studied, and explicit characterisations of the Bayesian D ...
Konstantinou, Maria, Dette, Holger
openaire   +5 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Can Pre-Storm Errors in the Low-Level Inflow Help Predict Spatial Displacement Errors in MCS Initiation?

Atmosphere, 2020
The Great Plains low-level jet (LLJ) is a contributing factor to the initiation and evolution of nocturnal Mesoscale Convective Systems (MCSs) in the central United States by supplying moisture, warm air advection, and a source of convergence.
Nicholas J. Vertz, William A. Gallus, Brian J. Squitieri   +2 more
doaj   +1 more source

An $\{l_1,l_2,l_{\infty}\}$-Regularization Approach to High-Dimensional Errors-in-variables Models

, 2014
Several new estimation methods have been recently proposed for the linear regression model with observation error in the design. Different assumptions on the data generating process have motivated different estimators and analysis.
Belloni, Alexandre, Rosenbaum, Mathieu, Tsybakov, Alexandre B.   +2 more
core   +2 more sources

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Model-Robust Estimation of Multiple-Group Structural Equation Models

Algorithms, 2023
Structural equation models (SEM) are widely used in the social sciences. They model the relationships between latent variables in structural models, while defining the latent variables by observed variables in measurement models.
Alexander Robitzsch
doaj   +1 more source