Results 111 to 120 of about 2,308,308 (297)
Estimating the Intergenerational Correlation of Incomes : An Errors in Variables Framework [PDF]
Because the permanent incomes of parents and children are typically unobservable, the estimation of the intergenerational correlation of incomes is usually carried out via averaging methods or instrumentation.
Ramses H. ABUL NAGA
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Deconvolution Estimation in Measurement Error Models: The R Package decon
Journal of Statistical Software, 2011 Data from many scientific areas often come with measurement error. Density or distribution function estimation from contaminated data and nonparametric regression with errors in variables are two important topics in measurement error models.
Xiao-Feng Wang, Bin Wang
doaj
Fast and robust estimation of the multivariate errors in variables model. [PDF]
In the multivariate errors in variable models one wishes to retrieve a linear relationship of the form y = ß x + a, where both x and y can be multivariate. The variables y and x are not directly measurable, but observed with measurement error.
Croux, Christophe +2 more
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Analysis of errors in verbal fluency tasks in patients with chronic schizophrenia [PDF]
, 2016 Background and Objectives: Even if verbal fluency deficits have been described in Schizophrenia, error pattern in this test has not been analyzed in detail in the literature.
Bueno, Adrián Marcelo +4 more
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Estimating production functions with robustness against errors in the proxy variables [PDF]
This paper proposes a new semi-nonparametric maximum likelihood estimation method for estimating production functions. The method extends the literature on structural estimation of production functions, started by the seminal work of Olley and Pakes ...
Guofang Huang, Yingyao Hu
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Life-Cycle Variation in the Association between Current and Lifetime Earnings [PDF]
Researchers in a variety of important economic literatures have assumed that current income variables as proxies for lifetime income variables follow the textbook errors-in-variables model.
Gary Solon, Steven Haider
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