Extracts From Grapefruit (Citrus paradisi) Peel via Microwave-Assisted and Conventional Extractions: Evaluation of Nosema Infection and Toxicity in Honey Bees. [PDF]
Conventional and microwave‐assisted extractions of grapefruit peels were optimized using response surface methodology (RSM) based on TPC, TFC, and antioxidant activity (DPPH). The phytochemical profiles of the two optimum extracts were characterized via HPLC before evaluating their acute and chronic toxicity, as well as their effects on honey bee (Apis
Kaya MM +4 more
europepmc +2 more sources
Expressions of Kisspeptin System and Ki-67 in the Reproductive Tissues of Cyclic Bitches. [PDF]
ABSTRACT Kisspeptin is a peptide that plays a pivotal role in the central regulation of gonadotropins. It is regarded as a key regulator of reproductive processes, including follicular and luteal development and endometrial remodelling. The objective of this study was to investigate the expression of KISS1, its receptor KISS1R and the proliferation ...
Korkmaz Ağaoğlu Ö +4 more
europepmc +2 more sources
Optimization of Phenolic and Flavonoid Extraction From Bee Bread Using Response Surface Methodology and Central Composite Design, and Evaluation of Antimicrobial Activity. [PDF]
This study successfully optimized the extraction parameters for Turkish bee bread using Response Surface Methodology (RSM) with a Central Composite Design (CCD). Under optimized conditions (30°C, 40 mL/g ratio, 66.7% ethanol, 20 h), the recovery of total phenolics (26.86 mg GAE/g) and flavonoids was maximized.
Keyvan N +6 more
europepmc +2 more sources
Protective Effects of Hesperidin on Letrozole-Induced Neurotoxicity: Involvement of Oxidative Stress, Apoptotic Signaling, and Inflammation. [PDF]
Letrozole induces neurotoxicity by promoting oxidative stress, inflammation, and apoptotic signaling in the brain. Hesperidin co‐treatment mitigates these effects by restoring redox balance, suppressing pro‐inflammatory cytokines, and normalizing Bax/Bcl‐2–mediated apoptotic pathways, thereby exerting neuroprotective effects.
Ayhan İ +4 more
europepmc +2 more sources
A Comparative Analysis of Deep Convolutional Networks for Automated Diagnosis of Retinal Detachment in Dogs. [PDF]
ABSTRACT Objective To compare ImageNet‐pretrained deep convolutional neural networks for automated detection of retinal detachment (RD) in canine fundus photographs. Animals Studied Archived fundus images from 275 dogs. Procedures In this multicenter retrospective study, 2000 color fundus photographs (793 RD; 1207 normal) acquired between 2020 and 2025
Okur S +7 more
europepmc +2 more sources
Reevaluating the Need for Routine IGF-1 Screening in Poorly Controlled Type 2 Diabetes Mellitus. [PDF]
In 504 patients with poorly controlled type 2 diabetes (HbA1c > 8%), routine IGF‐1 screening identified elevated levels in only 0.39%. No patient fulfilled biochemical or clinical criteria for acromegaly after confirmatory testing. Routine IGF‐1 screening in poorly controlled diabetes has limited diagnostic yield and should be reserved for clinical or ...
Sonmez MT +7 more
europepmc +2 more sources
İslam ülkelerinde tıpkı Muhammed İkbal gibi"Şairü'l-İslam" lakabıyla tanınan Âkif’in bugüne kadar hayatı,düşünceleri, eserleri, şahsiyeti, İslam ümmeti için verdiği mücadele pek çokaraştırmaya konu olmuştur.
Yılmaz Daşcıoğlu, Amira Husseiny
doaj +1 more source
Mutsuz eden yöneticilerden beklenen liderlik tarzları üzerine senaryo araştırması
Bu çalışmanın amacı çalışanların işyerlerinde yöneticilerinin davranışlarından kaynaklı oluşan mutsuzluklarının hangi liderlik tarzı ile giderilebileceğini tespit edebilmektir.
Dorukcan Pehlivan +3 more
doaj +1 more source
Bu çalışmanın amacı üniversiteler arası spormüsabakalarına katılan muay thai sporcularının şiddet eğilimlerinin değerlendirilmesineyöneliktir.
Mehmet Haşim Akgül +3 more
doaj +1 more source
Mehmet Akif Ersoy: Tanrı, İnsan ve Eylem
Mehmet Akif Ersoy’u şair kimliğinden ziyade düşünür kimliğiyle ele alan Yazar Ali yıldırım Mehmet Akif Ersoy Tanrı, İnsan ve Eylem isimli eserinde Akif’in Tanrı-alem ve Tanrı-insan ilişkisine yönelik görüşlerini ele almaktadır. Aynı zamanda kitapta süreç
Asım Kaya
doaj

