Results 81 to 90 of about 21,163 (261)

Characterization of CD123 expression by mast cells in systemic mastocytosis with multicolor flow cytometry

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract Systemic mastocytosis (SM) is a clonal mast cell (MC) disorder characterized by aberrant immunophenotypes, including expression of CD25, CD2, and occasionally CD30. CD123, the α‐subunit of the interleukin‐3 receptor, is a therapeutic target in hematologic malignancies and has been reported to be expressed on neoplastic MCs by ...
Ryan C. Shean   +2 more
wiley   +1 more source

Case Report: Pancreatic Paraganglioma Mimicking a Well‐Differentiated Neuroendocrine Tumor: The Importance of Cytokeratin Immunohistochemistry

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Paragangliomas (PGLs) are uncommon neuroendocrine tumors most commonly found in the head and neck that originate from neural crest cells. Primary pancreatic paraganglioma is exceedingly rare and has largely been described in case reports and small case series. We present the case of a 79‐year‐old woman with an incidental pancreatic head lesion
Tanner Storozuk, Marc Vecchio
wiley   +1 more source

Utility of Fine Needle Aspiration Supernatant for Real‐Time PCR–Based Mutation Analysis in Non–Small Cell Lung Cancer

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Background The emergence of personalized therapy and molecular sequencing has significantly transformed the management of advanced non–small cell lung carcinoma (NSCLC). Supernatants obtained from fine needle aspiration (FNA) have been shown to be a reliable source of high‐quality nucleic acid for molecular testing.
Adeyinka Akinsanya   +9 more
wiley   +1 more source

The impact of forced closure on proppant distribution of hydraulic fracturing in shale formations

open access: yesDeep Underground Science and Engineering, EarlyView.
Research findings demonstrate that implementing forced closure within shale formations can remarkably mitigate proppant settlement, concurrently increasing the effective propped surface area from 29.74% to 38.68%. Abstract Forced closure is widely used in conventional oil and gas reservoirs to promote uniform proppant placement.
Tongxuan Gu   +3 more
wiley   +1 more source

Uniaxial compressive strength prediction and ratio parameter optimization of titanium tailings composite backfill materials using intelligent hybrid models

open access: yesDeep Underground Science and Engineering, EarlyView.
Based on the 90 datasets, ERT and four optimization algorithms were used to build four hybrid models to predict the UCS of the backfill body. The SMA‐ERT model was the most effective model, and it can reliably guide the design of the backfill ratio parameters. Abstract This study analyzed the feasibility of using titanium (Ti) tailings as a backfilling
Weijun Liu, Zida Liu, Zhixiang Liu
wiley   +1 more source

Exponentially‐constrained Gaussian mixture model for quantifying vertical development of water‐conducting fracture zones in lithologically stratified mining roofs

open access: yesDeep Underground Science and Engineering, EarlyView.
This study proposes an exponentially‐constrained Gaussian mixture model (EcGMM) to quantify vertical fracture heterogeneity in stratified roof strata. The model integrates a piecewise exponential decay term capturing global stress dissipation with Gaussian components representing localized fracture intensification at lithological interfaces.
Huiqing Yuan   +5 more
wiley   +1 more source

Analysis of triggering factors of debris flows and conditions for possible reactivation: Case study of the Lemešná Mountain in the Javorníky Range, Czech Republic

open access: yesMoravian Geographical Reports
On 2nd June 2010, heavy rainfall triggered a significant debris flow on the southern slope of Lemešná Mountain in the Javorníky Range (Outer Western Carpathians), Czech Republic.
Smolíková Jana   +7 more
doaj   +1 more source

Antibodies to recombinant human alpha-L-iduronidase prevent disease correction in cortical bone in MPS I mice

open access: yesMolecular Therapy: Methods & Clinical Development
Mucopolysaccharidosis I (MPS I) is a lysosomal storage disorder caused by deficiency of the enzyme α-l-iduronidase (IDUA). Failure of enzyme replacement therapy (ERT) to treat skeletal disease may be due to development of anti-IDUA antibodies, found ...
Sarah C. Hurt   +5 more
doaj   +1 more source

Comparative Analysis of Metal Preloading Technologies in Batteries and Capacitors

open access: yesEcoEnergy, EarlyView.
Metal preloading strategies play an important role in efficient batteries and hybrid capacitors to compensate for the consumed metals at the first discharge. This article reviews recent progress in preloading technologies in lithium‐ion and other metal‐ion systems.
Xuexue Pan   +3 more
wiley   +1 more source

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