Results 91 to 100 of about 227,154 (335)

Ultraviolet-induced inflammation: Validation of the PI-MED erythema measure and its associations with anhedonia [PDF]

open access: green, 2022
Holly Sullivan‐Toole   +6 more
openalex   +1 more source

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

open access: yesAdvanced Science, EarlyView.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen   +8 more
wiley   +1 more source

Reprogramming M2b Macrophages via GPX1 Activation by Selenium Nanoparticles Attenuates Lupus Nephritis

open access: yesAdvanced Science, EarlyView.
SeZM NPs selectively target M2b macrophages through mannose–MRC1 (CD206) recognition, enhance GPX1 biosynthesis, and suppress mitochondrial ROS generation, oxidative stress, and JAK–STAT signaling. This dual regulation reduces pro‐inflammatory cytokine release, limits immune cell infiltration and fibrosis, and preserves renal function, providing a ...
Haoran Lv   +16 more
wiley   +1 more source

Mepyramine targets mutant Nav1.7 channels to relieve pain and erythema in primary erythromelalgia patients

open access: yesFrontiers in Medicine
Gain-of-function mutations in SCN9A, which encodes the Nav1.7 voltage-gated sodium channel, are known to cause primary erythromelalgia (PEM). This condition is characterized by recurrent episodes of erythema, burning pain, and warmth in the extremities ...
Myriam Ducrocq   +9 more
doaj   +1 more source

A Microfiber‐Reinforced Janus Hydrogel E‐Skin With Recyclable Feature for Multimodal Sensing and Gender‐Specific Physiological Monitoring

open access: yesAdvanced Science, EarlyView.
Hydrogel‐based wearable electronics hold great promise for physiological monitoring in privacy‐sensitive regions. In this study, a polyurethane (PU) microfiber‐reinforced gelatin hydrogel e‐skin is developed, boasting multiple advantages such as ultra‐thinness, high toughness, and long‐term skin conformability.
Yarong Ding   +11 more
wiley   +1 more source

Long-term safety and efficacy of trifarotene 50 μg/g cream, a first-in-class RAR-γ selective topical retinoid, in patients with moderate facial and truncal acne. [PDF]

open access: yes, 2020
BackgroundTreatment for both facial and truncal acne has not sufficiently been studied.ObjectivesTo evaluate the long-term safety and efficacy of trifarotene in both facial and truncal acne.MethodsIn a multicentre, open-label, 52-week study, patients ...
Ahmad, F   +11 more
core  

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

open access: yesAdvanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li   +7 more
wiley   +1 more source

Seamlessly Overcoming Biological Barriers with a Small Photosensitizer to Treat Metastatic Tumors with Photodynamic Therapy

open access: yesAngewandte Chemie, EarlyView.
LUZ 51 is a relatively small and amphiphilic photosensitizer that accumulates in poorly‐vascularized tumors, is rapidly internalized by cancer cells, does not elicit skin photosensitivity and triggers robust immunological responses that reduce spontaneous metastasis.
Mafalda Penetra   +7 more
wiley   +2 more sources

Synthesis and characterization of a polyurethane carrier used for a prolonged transmembrane transfer of a chili pepper extract

open access: yesInternational Journal of Nanomedicine, 2018
Livia-Cristina Borcan,1,* Zoltan Dudas,2,3,* Adel Len,2,4 Janos Fuzi,2,4 Florin Borcan,5 Mirela Cleopatra Tomescu1 1The 5th Department (Internal Medicine I), Faculty of Medicine, “Victor Babes” University of Medicine and Pharmacy, Timisoara,
Borcan LC   +5 more
doaj  

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