Results 141 to 150 of about 279,200 (380)

Safety, Tolerability, and Pharmacokinetics of the Long‐Acting SARS‐CoV‐2–Neutralizing Monoclonal Antibody Combination AZD7442 (Tixagevimab/Cilgavimab) in Healthy Chinese Adults

Clinical Pharmacology in Drug Development, EarlyView.
Abstract AZD7442, a combination of extended half‐life monoclonal antibodies tixagevimab and cilgavimab, was shown to neutralize previously circulating SARS‐CoV‐2 variants. This study evaluated safety, tolerability, pharmacokinetics, and pharmacodynamics of AZD7442 in healthy Chinese adults. In this randomized, placebo‐controlled, Phase 1 study, AZD7442
Nanyang Li, Jing Zhang, Wenhong Zhang, Zhongyuan Xu, Xiangcao Yao, Anqi He, Shuyuan Liu, Xiaoyun Ge, Jinxi Liu, Yunfei Li, Cecil Chi‐Keung Chen, Huixia Zhang   +11 more
wiley   +1 more source

Erythema Gyratum Repens (Gammel, 1952) [PDF]

, 1959
J. Schneeweiss, S. C. Gold
openalex   +1 more source

An evaluation of properties related to wear time of four dressings during a five-day period [PDF]

, 2015
This study evaluated skin tolerance and other properties relating to wear time, such as conformability and comfort, pain on dressing removal, adhesion and premature detachment, of four advanced hydrated dressings applied to the knees and elbows of 22 ...
Bielfeldt, Stephen, Rippon, Mark, Waring, Mike   +2 more
core  

Profiling a Neo‐Antigen‐Driven Immune Response in Healthy Volunteers: A Randomized, Double‐Blind, Placebo‐Controlled Study of the KLH Challenge Model

Clinical Pharmacology &Therapeutics, EarlyView.
Novel compounds targeting the adaptive immune system are commonly initially investigated in healthy volunteers (HV). HV frequently lack constitutively expressed drug‐target engagement biomarkers, complicating the evaluation of pharmacological activity. The keyhole limpet hemocyanin (KLH) neo‐antigen challenge elicits a controlled immune response in HV ...
Micha N. Ronner, Hendrika W. Grievink, Mahdi Saghari, Michelle Osse, Thierry P.P. van den Bosch, Jeffrey Damman, Marieke L. de Kam, Jacobus Burggraaf, Naomi B. Klarenbeek, Manon A. A. Jansen, Matthijs Moerland   +10 more
wiley   +1 more source

AN ANOMALOUS CASE OF ERYTHEMA MULTIFORME IN A PATIENT WITH CARDIAC AND RENAL DISEASE [PDF]

, 1903
Arthur Whitfield
openalex   +1 more source

Health‐Related Quality of Life in Patients With a Head and Neck Sarcoma: A Mixed‐Methods Study

Head &Neck, EarlyView.
ABSTRACT Background Patients with head and neck sarcomas (HNS) face unique health‐related quality of life (HRQoL) challenges due to its disease rarity. This study examined and identified the prevalence of generic‐ and location‐specific HRQoL issues.
E. Koffi, C. S. Padilla, C. Drabbe, W. H. Schreuder, C. Zemouri, D. den Hollander, D. J. Grünhagen, S. Sodergren, S. Singer, R. L. Jones, I. M. E. Desar, L. Fauske, M. Pinto, I. Nixon, S. Salah, Ø. S. Bruland, V. L. M. N. Soomers, M. A. J. van de Sande, J. J. de Haan, C. Verhoef, L. C. Steggink, W. J. van Houdt, T. I. Bootsma, M. T. Tesselaar, W. T. A. van der Graaf, O. Husson   +25 more
wiley   +1 more source

Assessment of diagnosis of inflammatory breast cancer cases at two cancer centers in Egypt and Tunisia

Cancer Medicine, 2013
The diagnosis of inflammatory breast cancer (IBC) is largely clinical and therefore inherently somewhat subjective. The objective of this study was to evaluate the diagnosis of IBC at two centers in North Africa where a higher proportion of breast cancer
Catherine Schairer, Amr S. Soliman, Sherif Omar, Hussein Khaled, Saad Eissa, Farhat Ben Ayed, Samir Khalafallah, Wided Ben Ayoub, Elizabeth D. Kantor, Sofia Merajver, Sandra M. Swain, Mitchell Gail, Linda Morris Brown   +12 more
doaj   +1 more source

Surgical site infections and sepsis in gynecological surgery

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Despite advancements in infection control, surgical site infections (SSIs) and postoperative sepsis remain significant challenges in gynecological surgery, contributing to increased morbidity, mortality, and healthcare costs. In low‐income countries, circulatory failure due to septic shock leads to most deaths after surgery, with sepsis ...
Cristina Taliento, Gennaro Scutiero, Carmelia Milano, Mattia Grasso, Francesca Nitti, Orsola Brasile, Ruby Martinello, Giulia Bernardi, Stefano Restaino, Martina Arcieri, Matteo Pavone, Nicolò Bizzarri, Giuseppe Vizzielli, Pantaleo Greco   +13 more
wiley   +1 more source

Erythema Marginatum as an Unusual Presentation for Kawasaki Disease

پزشکی بالینی ابن سینا, 2008
Introduction: Kawasaki disease is an acute, systemic vacuity that predominantly manifests in infants and young children. Severe systemic inflammation and vacuities can cause cardiovascular involvement, particularly coronary artery injury that includes ...
Iraj Sedighi, Hasan Bazmamoun, Ali Amanati   +2 more
doaj  

Dynamic Ultrasound Imaging of Extensor Pollicis Brevis Hypertrophy in Proximal Intersection Syndrome: A Case Report and Literature Review

Journal of Clinical Ultrasound, EarlyView.
Dynamic ultrasound revealed extensor pollicis brevis hypertrophy displacing second compartment tendons, suggesting a novel friction‐based mechanism for proximal intersection syndrome. This case highlights the role of dynamic sonography in identifying motion‐dependent tendon interactions underlying overuse‐related wrist pain.
Daoukas Stavros, Galanis Dimitrios, Mathew Benoy, Malliaropoulos Nikos   +3 more
wiley   +1 more source