Results 41 to 50 of about 212,870 (341)
Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function
Advanced Functional Materials, EarlyView.Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh +3 more
wiley +1 more source
Diagnostics, 2021 Background: This paper demonstrates the use of optical diagnostic methods to assess the dynamic skin changes observed in acute and chronic exposure to ultraviolet (UV) radiation in vivo.
Dmitry Kulikov +8 more
doaj +1 more source
Salt‐Compact Albumin as a New Pure Protein‐based Biomaterials: From Design to In Vivo Studies
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.A new class of materials built entirely of native albumin protein is designed using a simple protocol based on salt‐assisted compaction, breaking with current crosslinking strategies. This green process leads, surprisingly, to water‐insoluble handable materials with high preservation of their native protein structures and Young's modulus close to that ...
Eya Aloui +19 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.A dual‐head airbrush‐based spraying device, combined with a fibrinogen bioink enriched with glycosaminoglycans and collagen, enables the delivery of biomaterials and cells to promote wound healing. This system demonstrates effective skin regeneration in vitro and in vivo, with comparable results to autografts.
Paula Pleguezuelos‐Beltrán +7 more
wiley +1 more source
Mini erythema migrans - A sign of early Lyme borreliosis [PDF]
, 2006 Background: An erythema migrans (EM) remaining smaller than 5 cm in diameter, called mini EM by us, has not been addressed in detail. Objective: To study the significance of the mini EM as a sign of Lyme borreliosis. Methods: Patients with suspected mini
Weber, K., Wilske, B.
core +1 more source
Rolling Ultrasharp Microneedle Spheres Enable Topical Delivery of Biologics Through the Skin
Advanced Healthcare Materials, EarlyView.Rolling ultraminiaturized microneedle spheres (RUMS), created via two‐photon polymerization, unlock effective and painless topical delivery of messenger RNA (mRNA) and drugs through the skin. By gently forming thousands of microscopic pores, RUMS boost skin permeability by up to 100‐fold.
Theocharis Nikiforos Iordanidis +6 more
wiley +1 more source
Clinical Trial of Low Irritative Skin Care Cosmetics in Japanese Subjects with Dry Skin
Clinical, Cosmetic and Investigational Dermatology, 2020 Kazunori Tanaka,1 Teruaki Nagasawa,1 Yuko Nomura,2 Yoshiki Kubota,1 Akihiko Miyake,1 Kimio Kawamura,1 Yoko Yamaguchi1 1Pharmaceutical Products Research and Development Section, NANOEGG® Research Laboratories, Inc, Kawasaki, Kanagawa, Japan; 2Nomura ...
Tanaka K +6 more
doaj
Frontal Fibrosing Alopecia: An Observational Single-Center Study of 306 Cases
Life, 2023 (1) Background: Frontal fibrosing alopecia (FFA) is a scarring alopecia that predominantly affects postmenopausal women; (2) Methods: A retrospective, observational, single-center study was conducted in the Hospital General Universitario in Ciudad Real ...
Marcos Carmona-Rodríguez +4 more
doaj +1 more source
Safety Evaluation of Repeated Application of Polymeric Microarray Patches in Miniature Pigs
Advanced Healthcare Materials, EarlyView.This study demonstrates the safety of repeated application of three types of microarray patches (MAPs), hydrogelforming, dissolving, and implantable, over four weeks in miniature pigs. No adverse skin or systemic effects were observed, supporting the clinical potential of MAPs as safe and effective drug delivery platforms.
Qonita Kurnia Anjani +4 more
wiley +1 more source