Results 71 to 80 of about 134,651 (307)

Expert Perspectives on a Clinical Challenge: Hematologic Malignancies and Vasculitis

Arthritis &Rheumatology, Accepted Article.
Systemic vasculitis describes a collection of rare diseases each caused by inflammation of blood vessel walls that can cause severe systemic complications [[3, 4]](#ref‐0003). The pattern of vascular inflammation and resultant damage is frequently variable and may be mimicked, or directly triggered, by infection or malignancy.
Michelle L. Robinette, Hetty E. Carraway
wiley   +1 more source

Dermatopathologic emergencies part ii: Dermatopathologic and situational

Indian Journal of Dermatopathology and Diagnostic Dermatology, 2018
In dermatopathology, there are several conditions which must be addressed emergently. While some conditions necessitate emergent intervention because of the pathology of the cutaneous manifestations, others require recognition of the underlying serious ...
Douglas H Atmatzidis, Amy R Weiss, Karl Hoegler, W Clark Lambert   +3 more
doaj   +1 more source

Gout and NLRP3 inflammasome biology

Arthritis &Rheumatology, Accepted Article.
This review describes the three broad stages of acute inflammation in the context of gout: initiation, leucocyte mobilisation, and self‐resolution. A typical case of a gout flare is presented. The role of the NLRP3 inflammasome in acute monosodium urate crystal‐induced inflammation is reviewed in detail.
Raewyn Poulsen, Nicola Dalbeth
wiley   +1 more source

Narrow-Band Reflectance Spectrophotometry for the Assessment of Erythematous and Hyperpigmented Skin Lesions in Localized Scleroderma: A Preliminary Study

Clinical, Cosmetic and Investigational Dermatology, 2021
Michal Szczepanek, Aleksandra Frątczak, Anna Lis-Święty Department of Dermatology, School of Medicine in Katowice, Medical University of Silesia, Katowice, PolandCorrespondence: Anna Lis-ŚwiętyDepartment of Dermatology, School of Medicine in Katowice ...
Szczepanek M, Frątczak A, Lis-Święty A   +2 more
doaj  

Efficacy and Safety of ABBV‐154 for the Treatment of Active Rheumatoid Arthritis: A Phase 2b, Randomized, Placebo‐Controlled Trial

Arthritis &Rheumatology, Accepted Article.
Objective Despite availability of biologics and targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) to treat rheumatoid arthritis (RA), many patients do not experience optimized disease control. Glucocorticoids are effective but have safety risks.
Frank Buttgereit, Atul Singhal, Alan Kivitz, Edit Drescher, Yoshinori Taniguchi, Rosalía Martínez Pérez, Jaclyn Anderson, Ronilda D'Cunha, Weihan Zhao, Nicholas DeVogel, Julie Parmentier, Romy Christmann, Dilek Arikan, Howard Amital   +13 more
wiley   +1 more source

The effect of severe renal impairment on the pharmacokinetics, safety and tolerability of balcinrenone

British Journal of Clinical Pharmacology, EarlyView.
Aims The aim of this phase 1 trial was to assess the pharmacokinetics, safety and tolerability of balcinrenone (previously AZD9977) in participants with severe renal impairment vs. those with normal renal function. Methods Participants with severe renal impairment (estimated glomerular filtration rate [eGFR] < 30 mL/min/1.73 m2) not on dialysis were ...
Chandrali S. Bhattacharya, Hans Ericsson, Susanne Johansson, Joanna Parkinson, Simina M. Boca, Ye Yang, Maria Heijer, Greggory Housler, Maria Leonsson‐Zachrisson, Judith Hartleib‐Geschwindner, Patricia Ely Pizzato   +10 more
wiley   +1 more source

A phase II basket trial of dual anti‐CTLA‐4 and anti‐PD‐1 blockade in rare tumors (DART) SWOG S1609: durable responses and delayed pseudoprogression in small cell carcinoma of the ovary, hypercalcemic type cohort

Cancer Communications, EarlyView.
Abstract Background The combined use of anti‐programmed cell death protein 1 (PD‐1)/anti‐cytotoxic T‐lymphocyte associated protein 4 (CTLA‐4) checkpoint inhibitors has been effective in various cancer types. The Southwest Oncology Group (SWOG) Dual Anti‐CTLA‐4 and Anti‐PD‐1 Blockade in Rare Tumors (DART) S1609 study investigated ipilimumab and ...
Young Kwang Chae, Megan Othus, Sandip Pravin Patel, Raid Aljumaily, Khine Z. Win, Tanya Pejovic, Sajeve S. Thomas, William R. Robinson III, Hye Sung Kim, Liam Il‐Young Chung, Christine M. McLeod, Helen X. Chen, Elad Sharon, Howard Streicher, Christopher W. Ryan, Charles D. Blanke, Razelle Kurzrock   +16 more
wiley   +1 more source

Glazy Erythema on Glans Penis in a 3-year-old Child: An Unusual Diagnosis of Zoon’s Balanitis Aided by Dermoscopy

Indian Dermatology Online Journal
Zoon’s balanitis is a benign inflammatory non-venereal genital dermatosis occurring in males. Cayenne pepper spots, a characteristic feature of Zoon’s balanitis, present as erythematous macule with red, pinpoint-like dots. Uncircumcised males between the
Bhumesh K. Katakam, Kalimi V. Udhayini, Sudharani Chintagunta, Hitha A. James   +3 more
doaj   +1 more source

The wingspan suspension approach: A modified semilunar technique for multiple areas of recession

Clinical Advances in Periodontics, EarlyView.
Abstract Background Gingival recession can be considered an undesirable condition that results in the exposure of the root surface. There are many techniques that can be employed to address gingival recession; however, they frequently involve a second surgical site.
Allison N. Rascon, Bradley Lander, Joseph P. Fiorellini, Rodrigo Neiva   +3 more
wiley   +1 more source

Fixed Drug Eruption with Pigmentation Induced by Etoricoxib: A Case Report

Iatreia
Fixed drug eruption with pigmentation is characterized by the appearance of erythematous or bullous lesions following the ingestion of certain medications.
Dextre-Vilchez, Sergio Armando, Ríos-Lozano, María Lucía   +1 more
doaj   +1 more source