Fetal Abnormalities of Metabolic Origin [PDF]
The subject of my discussion is prenatal diagnosis of genetic disorders of a metabolic rather than a chromosomal nature. Whereas the chromosomal defects are the result of either the transmission of a translocated chromosome from a single parent to its ...
Mamunes, Peter
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EGFRvIV: a previously uncharacterized oncogenic mutant reveals a kinase autoinhibitory mechanism [PDF]
Tumor cells often subvert normal regulatory mechanisms of signal transduction. This study shows this principle by studying yet uncharacterized mutants of the epidermal growth factor receptor (EGFR) previously identified in glioblastoma multiforme, which ...
AJ Ekstrand +43 more
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Enfermedad hemolítica perinatal Perinatal hemolytic disease
La enfermedad hemolítica perinatal (EHPN) es una afección inmunológica aloinmune contra antígenos de origen paterno presentes en los hematíes fetales y del recién nacido. Se han reportado numerosos aloanticuerpos dirigidos contra antígenos eritrocitarios
María del Rosario López de Roux +1 more
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Retroviral Expression of Transforming Growth Factor-Alpha Does Not Transform Fibroblasts or Keratinocytes [PDF]
Transforming growth factor α (TGFα) is a peptide so named because it helps to impart anchorage-independent growth to normal rat kidney (NRK) cells in vitro and is secreted by many rodent and human tumor cells.
Eric Finzi +48 more
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La predicción prenatal de la enfermedad hemolítica del feto y el recién nacido (EHFRN) y la severidad de esta, por métodos no invasivos, es de gran importancia para la adopción temprana de medidas que eviten o minimicen el daño fetal.
María Elena Alfonso Valdés +7 more
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Effectiveness of EGFR/HER2-targeted drugs is influenced by the downstream interaction shifts of PTPIP51 in HER2-amplified breast cancer cells [PDF]
Breast cancer is the most common female cancerous disease and the second most cause of cancer death in women. About 20-30% of these tumors exhibit an amplification of the HER2/ErbB2 receptor, which is coupled to a more aggressive and invasive growth of ...
Brobeil, Alexander +4 more
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Fetal renal artery flow and renal echogenicity in the chronically hypoxic state. [PDF]
peer reviewedThe object of this study was to investigate the fetal renal arterial blood flow in normal and hyperechogenic kidneys during the third trimester of gestation. The pregnancies screened were all chronically hypoxic. Depending on the etiology of
Suranyi, Andrea +7 more
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The regulation of matrix metalloproteinases and their inhibitors [PDF]
The matrix metalloproteinases (MMP) are a family of 23 enzymes in man. These enzymes were originally described as cleaving extracellular matrix (ECM) substrates with a predominant role in ECM homeostasis, but it is now clear that they have much wider ...
Clark, Ian M. +3 more
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Increased placental resistance and late decelerations associated with severe proteinuric hypertension predicts poor fetal outcome [PDF]
CITATION: Pattinson, R. C. et al. 1989. Increased placental resistance and late decelerations associated with severe proteinuric hypertension predicts poor fetal outcome.
Kirsten, G. +4 more
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Recent advances in the management of neonatal jaundice [PDF]
Jon F Watchko Division of Newborn Medicine, Department of Pediatrics, University of Pittsburgh School of Medicine, Magee-Womens Research Institute, Pittsburgh, PA, USA Abstract: Advances in the clinical assessment strategies used to identify neonates at
Watchko, Jon
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