Results 121 to 130 of about 825,332 (294)
Advanced Science, EarlyView.Engineered phage‐based trifunctional nanofibers are developed for synergistic biofilm eradication. Biofilm‐binding phages, armed with AuNPs and TCPP, serve as both warheads and scaffolds, endowing the phototherapy agents with biofilm‐anchoring ability. Upon light irradiation, AuNPs induce photothermal therapy, while TCPP generates 1O2 for photodynamic ...
Ying Cao +9 more
wiley +1 more source
Optimization of B Cell Responses in Human Immune System Mice Through Organoid Based Screening
Advanced Science, EarlyView.Human immune system (HIS) mice show limited B cell responses to immunization. Using HIS mouse spleen organoids, this study identifies cytokine combinations and innate immune signals that drive human B cell expansion, differentiation, and class‐switch. Applying these signals in vivo through temporal separation enables antigen‐specific IgG responses and ...
Haiqiao Sun +6 more
wiley +1 more source
Multimodal Imaging Reveals Rapid Catecholamine Uptake and Release by Neutrophils
Advanced Science, EarlyView.We show that immune cells (neutrophils) synthesize, uptake, and store catecholamine neurotransmitters such as dopamine or adrenaline. They also release them in response to specific stimuli (serotonin), which we directly visualize using fluorescent nanosensors. We further demonstrate that catecholamines affect neutrophil functions (NETosis) and platelet
Jennifer Mohr +19 more
wiley +1 more source
Validated formulae for estimation of whole blood viscosity underestimate the influence of erythrocyte aggregation and deformability. [PDF]
Ther Adv Cardiovasc Dis, 2016 Weidman J, Sloop G, St Cyr JA.
europepmc +1 more source
Thermochemical Micro‐Explosion for Prompt Thrombolysis via Proximal Injection of Liquid Alkali Metal
Advanced Science, EarlyView.We report a micro‐explosive thermochemical thrombolysis (METCT) therapy via injectable liquid alkali metal encapsulated in dimethyl silicone (LAM@oil). METCT enables prompt and safe vascular recanalization within 90 s. Critically, the LAM@oil system demonstrates significantly higher thrombolytic efficacy compared to clinically available thrombolytic ...
Xin Liao +7 more
wiley +1 more source
International Journal of Nanomedicine, 2018 Filomena A Carvalho,1,* Ana Filipa Guedes,1,* Cedric Duval,2 Fraser L Macrae,2 Luke Swithenbank,2 David H Farrell,3 Robert AS Ariëns,2 Nuno C Santos1 1Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal;
Carvalho FA +7 more
doaj
Advanced Science, EarlyView.ABSTRACT Infected diabetic wounds are sustained by a vicious cycle of hyperglycemia‐driven bacterial infection, persistent oxidative stress, and excessive inflammation, which collectively disrupt the ordered progression of tissue repair. Here, we engineered a stage‐adaptive Janus microneedle patch (MN‐FeSAC‐PPE) to enable a staged therapeutic process ...
Mengting Yin +13 more
wiley +1 more source
Aggregation of erythrocytes in burn disease.
International journal of burns and trauma, 2012 The manuscript describes experiments designed to examine factors that influence erythrocytes aggregation within the blood of burn patients. Results showed that the rate and degree of erythrocytes aggregation increased significantly in burn patients, and what is especially unfavorable for microcirculation, erythrocytes disaggregation decreased.
Grigory Y, Levin, Marpha N, Egorihina
openaire +1 more source
Aggregative properties of red blood cells platelets in young cattle in the first 10 days of life
RUDN Journal of Ecology and Life Safety, 2014 Objective: to establish features erythrocyte and platelet at healthy calfs in a phase newborn. The animals every day during the newborn phase determined aggregation cells using light microscopy and Visual mikrometod aggregation platelets. The results may
T A Belova +3 more
doaj
Advanced Science, EarlyView.ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin +16 more
wiley +1 more source