Results 151 to 160 of about 24,011 (296)

Selective Targeting of Immune Checkpoints HLA‐G and CD47 Using Novel Dual Signaling Protein DSP216 Promotes Innate Anticancer Immunity

Advanced Science, EarlyView.
The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob, Liat Tamir, Mufeed Abdeen, Ami Tamir, Alexandra Aronin, Itai Bloch, Roy Kahn, Iris Pecker, Mark Tykocinski, Gerwin Huls, Yaron Pereg, Ayelet Chajut, Edwin Bremer   +12 more
wiley   +1 more source

Agregasi Trombosit dan Laju Endap Darah pada Model Tikus Periodontitis (Platelet Aggregation and Erythrocyte Sedimentation Rate of Periodontitis Rat Model)

, 2019
Prosiding the 5th Dentistry Scientific Meeting of Jember, 2018Background: Periodontitis is one of periodontal disease, which is an infection or inflammation of the periodontal tissues.
Susilawati, I Dewa Ayu, Suhartini, Suhartini, Adji, Iman Santoso, Prasetya, Rendra Chriestedy   +3 more
core  

Validated formulae for estimation of whole blood viscosity underestimate the influence of erythrocyte aggregation and deformability. [PDF]

Ther Adv Cardiovasc Dis, 2016
Weidman J, Sloop G, St Cyr JA.
europepmc   +1 more source

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

Advanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng, Kaiwen Chen, Qiwei Ying, Shuya Wang, Xin Li, Guanlin Li, Yantao Zhao, Binghua Ma, Huanan Wang, Dawei Li, Lijun Zhang, Jian Zhang, Yu Zhao, Changle Ren, Baodong Chen, Yueming Song   +15 more
wiley   +1 more source

Erythrocyte aggregation kinetics for studying the vascular phase of inflammation in patients with suspected acute coronary syndrome or acute stroke. [PDF]

Sci Rep
Charansonney OL, Meseguer E, Goube P, Vicaut E.   +3 more
europepmc   +1 more source

A Chirality‐Converted Bacteriolytic Dodecapeptide Regulates Vibrio‐Induced Polymicrobial Infection and Ameliorates Invasion‐Associated Gut Microbiota Disequilibrium

Advanced Science, EarlyView.
Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng, Qipeng Cheng, Xiaoxu Zhang, Honglan Wang, Jinghan Zhang, Xinyi Ding, Pengfei Zhang, Lanhua Yi, Kwok‐Yin Wong, Kin‐Fai Chan, Sheng Chen, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

Fully Humanized Bispecific T Cell Engager Shows Potent Activity in Central Nervous System and Peripheral Tumors

Advanced Science, EarlyView.
This study reports the development of a fully humanized bispecific T cell engager targeting IL13RA2, a tumor‐associated antigen enriched in glioblastoma. This off‐the‐shelf immunotherapy drives potent, antigen‐dependent T cell activation and tumor killing, and prolongs survival in experimental GBM and other solid tumors models without detectable off ...
Joseph T. Duffy, Angela Martin‐Regalado, Benedikt E. Haupt, Jacob R. Pogue, Aditi Thakur, Manuel Fierro Cota, Markella Zannikou, Sol Misener, Vera P. Krymskaya, Kathleen McCortney, Jason Miska, Craig Horbinski, Dmitri Simberg, Maciej S. Lesniak, Charles D. James, Roger Stupp, Irina V. Balyasnikova   +16 more
wiley   +1 more source

Effects of lornoxicam and intravenous ibuprofen on erythrocyte deformability and hepatic and renal blood flow in rats

, 2016
Hande Arpacı,1,* Faruk Metin Çomu,2 Ayşegül Küçük,3 Bahadır Kösem,4 Seyfi Kartal,4 Volkan Şıvgın,5 Hüseyin Cihad Turgut,6,* Muhammed Enes Aydın,5 Derya Sebile Koç,5 Mustafa Arslan5 1Department of Oral and ...
Aydın ME, Arpacı H, Koç DS, Çomu FM, Küçük A, Kartal S, Turgut HC, Arslan M, Şıvgın V, Kösem B   +9 more
core  

Decreased erythrocyte aggregation in Glenn and Fontan: univentricular circulation as a rheologic disease model. [PDF]

Pediatr Res
Suriany S, Liu H, Cheng AL, Wenby R, Patel N, Badran S, Meiselman HJ, Denton C, Coates TD, Wood JC, Detterich JA.   +10 more
europepmc   +1 more source

Erythrocyte Aggregation before and after Haemodialysis [PDF]

Nephron, 2008
L, Houbouyan, J F, Stoltz, A, Beauchet, J, Prinseau, N, Consoli, L, Moulonguet-Doleris, A, Baglin, A, Goguel   +7 more
openaire   +2 more sources