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Erythrocytes deformability and diabetes
Clinical Hemorheology and Microcirculation, 1983A large scale study of the erythrocyte deformability in diabetes is presented. The initial filtration flow rate method is used on diluted (white blood cells reduced) RBC suspensions. The rigidity index thus obtained, IR, is largely insensitive to the filter plugging. A significant increase of IR is observed for diabetic patients (p
Hanss, M. +3 more
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Erythrocyte deformability and disease
Trends in Biochemical Sciences, 1982Abstract For human erythrocytes to endure their continual passage through the circulation for 120 days, they must remain deformable and flexible. Here we discuss the factors which may be responsible for premature cell death in some diseases.
Catherine A. Rice-Evans, Michael J. Dunn
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Effect of sphering on erythrocyte deformability
Biorheology, 1972The deformability of sphered erythrocytes produced in vitro by fragmentation loss of membrane in a glass micropipette or by heating at 48°C has been compared to spheres in metabolically depleted blood and in spheres from blood bank blood by measuring the pressure for passage through a 2.8-μ micropipette.
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Influence of erythrocyte deformability on circulation
Research in Experimental Medicine, 1973In an isolated perfused guinea pig liver the influence of low deformable erythrocytes on blood flow has been tested. Down to 30% reduced deformability of red cells resulted in a significant reduction of flow peculiarly at low pressures. Decrease of venous out-flow hematocrit at nearly normal liver weight indicated slowly circulating rigid red cells ...
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Erythrocyte deformability and microhematuria in children and adolescents
Pediatric Nephrology, 2003The aim of this study was to investigate whether erythrocyte deformability is higher in otherwise healthy children and adolescents with asymptomatic isolated glomerular microhematuria and no clinical or laboratory signs indicating renal disorder. Erythrocyte deformability in 33 children and adolescents with unexplained asymptomatic isolated glomerular ...
Anamarija, Meglic +4 more
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Microscopic investigation of erythrocyte deformation dynamics
Biorheology: The Official Journal of the International Society of Biorheology, 2006The understanding of erythrocyte deformation under conditions of high shear stress and short exposure time is central to the study of hemorheology and hemolysis within prosthetic blood contacting devices. A combined computational and experimental microscopic study was conducted to investigate the erythrocyte deformation and its relation to transient ...
Rui, Zhao +5 more
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Erythrocyte Deformation in Human Muscular Dystrophy
Science, 1974Erythrocytes from patients with congenital muscular dystrophy exhibit dramatic surface deformation when observed with a scanning electron microscope. A similar alteration, but one affecting a smaller proportion of cells, occurs in the case of female carriers of the sex-linked Duchenne dystrophic condition.
D W, Matheson, J L, Howland
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Erythrocyte Deformability in Uremic Hemodialyzed Patients
Annals of Internal Medicine, 1973Abstract Erythrocyte deformability was measured in normal people and in patients with chronic renal failure treated with hemodialysis.
S, Forman, M, Bischel, P, Hochstein
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Modulation of erythrocyte deformability by PKC activity
Clinical Hemorheology and Microcirculation, 2008The interactions between membrane, peripheral and cytoskeleton proteins are responsible for the maintenance of erythrocyte deformability (EEI) and some of these interactions are modulated by PKC activity. Protein band 3 of the erythrocyte membrane is phosphorylated by phosphotyrosine kinases (PTK) and dephosphorylated by phosphotyrosine phosphatase ...
De Oliveira, Sofia +2 more
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[Disorders of erythrocyte deformability].
Anesteziologiia i reanimatologiia, 1994The literature data on the disturbances of the deformability of erythrocyte membranes (DEM) in different conditions have been reviewed. The diseases characterized by reduced DEM have been enumerated. The causes of disturbed DEM have been indicated and the devices and methods investigating it have been outlined.
I I, Mishchuk +5 more
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