Results 11 to 20 of about 590,047 (329)

Metabolic Influences Modulating Erythrocyte Deformability and Eryptosis [PDF]

Metabolites, 2021
Many factors in the surrounding environment have been reported to influence erythrocyte deformability. It is likely that some influences represent reversible changes in erythrocyte rigidity that may be involved in physiological regulation, while others ...
Jean-Frédéric Brun, Emmanuelle Varlet-Marie, Justine Myzia, Eric Raynaud de Mauverger, Etheresia Pretorius   +4 more
doaj   +3 more sources

Erythrocyte Deformability and Na,K-ATPase Activity in Various Pathophysiological Situations and Their Protection by Selected Nutritional Antioxidants in Humans. [PDF]

Int J Mol Sci, 2021
The physicochemical and functional properties of erythrocytes are worsened in a variety of diseases. Erythrocyte deformability refers to their ability to adjust their shape according to external forces exerted against them in the circulation.
Radosinska J, Vrbjar N.
europepmc   +4 more sources

cAMP-Signalling Regulates Gametocyte-Infected Erythrocyte Deformability Required for Malaria Parasite Transmission. [PDF]

PLoS Pathog, 2015
Blocking Plasmodium falciparum transmission to mosquitoes has been designated a strategic objective in the global agenda of malaria elimination. Transmission is ensured by gametocyte-infected erythrocytes (GIE) that sequester in the bone marrow and at ...
Ramdani G, Naissant B, Thompson E, Breil F, Lorthiois A, Dupuy F, Cummings R, Duffier Y, Corbett Y, Mercereau-Puijalon O, Vernick K, Taramelli D, Baker DA, Langsley G, Lavazec C.   +14 more
europepmc   +12 more sources

Study of individual erythrocyte deformability susceptibility to INFeD and ethanol using a microfluidic chip. [PDF]

Sci Rep, 2016
Human red blood cells (RBCs) deformability in vitro was assessed during iron dextran (INFeD) loading and/or ethanol co-administration using microfluidic deformability screening. The results showed donor-specific variations in dose dependent deformability
Liu L, Huang S, Xu X, Han J.
europepmc   +4 more sources

Importance of Erythrocyte Deformability for the Alignment of Malaria Parasite upon Invasion. [PDF]

Biophys J, 2019
Invasion of erythrocytes by merozoites is an essential step for the survival and progression of malaria parasites. In order to invade red blood cells (RBCs), parasites have to adhere with their apex to the RBC membrane.
Hillringhaus S, Dasanna AK, Gompper G, Fedosov DA.   +3 more
europepmc   +2 more sources

Shear Stress Ameliorates Superoxide Impairment to Erythrocyte Deformability With Concurrent Nitric Oxide Synthase Activation. [PDF]

Front Physiol, 2019
The cellular deformability of red blood cells (RBC) is exceptional among mammalian cells and facilitates nutrient delivery throughout the microcirculation; however, this physical property is negatively impacted by oxidative stress.
Kuck L, Grau M, Bloch W, Simmonds MJ.
europepmc   +2 more sources

Plasmodium falciparum ligand binding to erythrocytes induce alterations in deformability essential for invasion [PDF]

eLife, 2017
The most lethal form of malaria in humans is caused by Plasmodium falciparum. These parasites invade erythrocytes, a complex process involving multiple ligand-receptor interactions.
Xavier Sisquella, Thomas Nebl, Jennifer K Thompson, Lachlan Whitehead, Brian M Malpede, Nichole D Salinas, Kelly Rogers, Niraj H Tolia, Andrea Fleig, Joseph O’Neill, Wai-Hong Tham, F David Horgen, Alan F Cowman   +12 more
doaj   +4 more sources

Effects of lornoxicam and intravenous ibuprofen on erythrocyte deformability and hepatic and renal blood flow in rats [PDF]

Drug Design, Development and Therapy, 2016
Hande Arpacı,1,* Faruk Metin Çomu,2 Ayşegül Küçük,3 Bahadır Kösem,4 Seyfi Kartal,4 Volkan Şıvgın,5 Hüseyin Cihad Turgut,6,* Muhammed Enes Aydın,5 Derya Sebile Koç,5 Mustafa Arslan5 1Department of Oral and ...
Arpacı H, Çomu FM, Küçük A, Kösem B, Kartal S, Şıvgın V, Turgut HC, Aydın ME, Koç DS, Arslan M   +9 more
doaj   +2 more sources

Effects of N-Acetylcysteine and N-Acetylcysteine Amide on Erythrocyte Deformability and Oxidative Stress in a Rat Model of Lower Extremity Ischemia-Reperfusion Injury [PDF]

Cardiology Research and Practice, 2020
N-acetylcysteine (NAC) is an antioxidant which works as a free radical scavenger and antiapoptotic agent. N-acetylcysteine-amide (NACA) is a modified form of NAC containing an amide group instead of a carboxyl group of NAC.
Gokhan Erol, Hakan Kartal, Faruk M. Comu, Erdem Cetin, Ertan Demirdas, Huseyin Sicim, Celal S. Unal, Celalettin Gunay, Bilgehan S. Oz, Cengiz Bolcal   +9 more
doaj   +2 more sources

Effect of picroside II on erythrocyte deformability and lipid peroxidation in rats subjected to hind limb ischemia reperfusion injury. [PDF]

Drug Des Devel Ther, 2016
Background Ischemia reperfusion injury (I/R) in hind limb is a frequent and important clinical phenomenon. Many structural and functional damages are observed in cells and tissues in these kinds of injuries. In this study, we aimed to evaluate the effect
Çomu FM, Kılıç Y, Özer A, Kirişçi M, Dursun AD, Tatar T, Zor MH, Kartal H, Küçük A, Boyunağa H, Arslan M.   +10 more
europepmc   +2 more sources